ArticleThe ISME journal2022
Expanding the phylogenetic distribution of cytochrome b-containing methanogenic archaea sheds light on the evolution of methanogenesis.
Article in The ISME journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23 citing papers in PubMed, 44 citations in OpenAlex.
- Comparative pangenome analysis of methanogenic archaea from diverse ecosystems reveals potential targets for methane mitigation in rumen microbiome.Journal of animal science and technology · 2026Article
- Enhancing Duck Manure Anaerobic Digestion with Hydrochar: Exploring Green Material Potential via Bidirectional AD-HTC Coupling.Materials (Basel, Switzerland) · 2026Article
- Oxygen reductase origin followed the great oxidation event and terminated the Lomagundi excursion.Biochimica et biophysica acta. Bioenergetics · 2026Article
- Targeted isolation of HNature protocols · 2026Review
- Diversity of Archaea.Progress in molecular and subcellular biology · 2026Review
- Cultivation of Methanonezhaarchaeia, the third class of methanogens within the phylum Thermoproteota.Science advances · 2025Article
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- Cryptic sulfur cycling in the deep biosphere of ferruginous Lake Towuti, Indonesia.Frontiers in microbiology · 2025Article
- Genome reduction in novel, obligately methyl-reducing Methanosarcinales isolated from arthropod guts (Methanolapillus gen. nov. and Methanimicrococcus).FEMS microbiology ecology · 2024Article
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- Oxygenation of Earth's atmosphere induced metabolic and ecologic transformations recorded in the Lomagundi-Jatuli carbon isotopic excursion.Applied and environmental microbiology · 2024Article
- New insights into the coal-associated methane architect: the ancient archaebacteria.Archives of microbiology · 2024Review
- Viral potential to modulate microbial methane metabolism varies by habitat.Nature communications · 2024Article
- Unraveling the phylogenomic diversity of Methanomassiliicoccales and implications for mitigating ruminant methane emissions.Genome biology · 2024Article
- Metabolic features that select for Bathyarchaeia in modern ferruginous lacustrine subsurface sediments.ISME communications · 2024Article
- A compendium of viruses from methanogenic archaea reveals their diversity and adaptations to the gut environment.Nature microbiology · 2023Article
- Electron transport chains as a window into the earliest stages of evolution.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
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16 authors at 6 institutions in 5 countries.
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Abstract
Methane produced by methanogenic archaea has an important influence on Earth's changing climate. Methanogenic archaea are phylogenetically diverse and widespread in anoxic environments. These microorganisms can be divided into two subgroups based on whether or not they use b-type cytochromes for energy conservation. Methanogens with b-type cytochromes have a wider substrate range and higher growth yields than those without them. To date, methanogens with b-type cytochromes were found exclusively in the phylum "Ca. Halobacteriota" (formerly part of the phylum Euryarchaeota). Here, we present the discovery of metagenome-assembled genomes harboring methyl-coenzyme M reductase genes reconstructed from mesophilic anoxic sediments, together with the previously reported thermophilic "Ca. Methylarchaeum tengchongensis", representing a novel archaeal order, designated the "Ca. Methylarchaeales", of the phylum Thermoproteota (formerly the TACK superphylum). These microorganisms contain genes required for methyl-reducing methanogenesis and the Wood-Ljundahl pathway. Importantly, the genus "Ca. Methanotowutia" of the "Ca. Methylarchaeales" encode a cytochrome b-containing heterodisulfide reductase (HdrDE) and methanophenazine-reducing hydrogenase complex that have similar gene arrangements to those found in methanogenic Methanosarcinales. Our results indicate that members of the "Ca. Methylarchaeales" are methanogens with cytochromes and can conserve energy via membrane-bound electron transport chains. Phylogenetic and amalgamated likelihood estimation analyses indicate that methanogens with cytochrome b-containing electron transfer complexes likely evolved before diversification of Thermoproteota or "Ca. Halobacteriota" in the early Archean Eon. Surveys of public sequence databases suggest that members of the lineage are globally distributed in anoxic sediments and may be important players in the methane cycle.
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