Evidence map›Paper›PMID 35810014›Full record

ArticleInternational dental journal2022

Evaluation of Fluoride Release in Chitosan-Modified Glass Ionomer Cements.

Cruz Nishanthine, Revathi Miglani, Indira R, Saravanan Poorni, Manali Ramakrishnan Srinivasan, Ali Robaian, Nassreen Hassan Mohammad Albar, Susen Faisal Rajeh Alhaidary, Sultan Binalrimal, Abdullah Almalki and 6 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in International dental journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
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  3. Evaluation of antibacterial efficiency ofJournal of Taibah University Medical Sciences · 2026
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  9. Frontiers in dental medicine · 2025
    Article
  10. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Cruz NishanthineDepartment of Conservative Dentistry and Endodontics, Sri Venkateswara Dental College and Hospital, Chennai, India.
Revathi MiglaniMig's Dental Care, Chennai, India.
Indira RRagas Dental College & Hospital, Uthandi, Chennai, India.
Saravanan PoorniDepartment of Conservative Dentistry and Endodontics, Sri Venkateswara Dental College and Hospital, Chennai, India.
Manali Ramakrishnan SrinivasanDepartment of Conservative Dentistry and Endodontics, Sri Venkateswara Dental College and Hospital, Chennai, India.
Ali RobaianDepartment of Conservative Dental Science, College of Dentistry, Prince Sattam bin Abdulaziz University, Alkharj, Saudi Arabia.
Nassreen Hassan Mohammad AlbarDepartment of Restorative Dental Sciences, College of Dentistry, Jazan University, Jazan, Saudi Arabia.
Susen Faisal Rajeh AlhaidaryDental Department, King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia.
Sultan BinalrimalRestorative Department, College of Dentistry, Riyadh Elm University, Riyadh, Saudi Arabia.
Abdullah AlmalkiDepartment of Preventive Dental Sciences, College of Dentistry, Majmaah University, AL-Majmaah, Saudi Arabia.
Thilla Sekar VinothkumarDepartment of Restorative Dental Sciences, College of Dentistry, Jazan University, Jazan, Saudi Arabia; Department of Conservative Dentistry and Endodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, India.
Harisha DewanDepartment of Prosthetic Dental Sciences, College of Dentistry, Jazan University, Jazan, Saudi Arabia.
Waseem RadwanRestorative Department, College of Dentistry, Riyadh Elm University, Riyadh, Saudi Arabia.
Mubashir Baig MirzaDepartment of Conservative Dental Science, College of Dentistry, Prince Sattam bin AbdulAziz University, Alkharj, Saudi Arabia.
Shilpa BhandiDepartment of Restorative Dental Sciences, College of Dentistry, Jazan University, Jazan, Saudi Arabia.
Shankargouda PatilDepartment of Maxillofacial Surgery and Diagnostic Science, Division of Oral Pathology, College of Dentistry, Jazan University, Jazan, Saudi Arabia. Electronic address: dr.ravipatil@gmail.com.
Jazan University · SAPrince Sattam Bin Abdulaziz University · SARiyadh Elm University · SAKing Fahd Armed Forces Hospital · SAMajmaah University · SARagas Dental College & Hospital · INSaveetha University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study assessed the influence of chitosan nanoparticles on the fluoride-releasing ability of 4 glass ionomer cement (GIC) through an in vitro analysis.

methodsFour types of GIC (type II light cure universal restorative, type II universal restorative, GC Fuji VII, and type IX) were modified with nanochitosan particles; 10% chitosan was added to the glass ionomer liquid. Six specimens for each of the 4 groups were created, using expendable Teflon moulds. Discs of each type of GIC (n = 6) were immersed in deionised water at various time intervals. Electrodes selective for fluoride ions were employed to analyse the amount of released fluoride at 1, 7, 14, 21, and 28 days.

resultsChitosan-modified GICs showed greater fluoride release than conventional GICs at all time points. All samples showed an initial high release of fluoride that tapered off with time. The total amount of fluoride released increased from the 1st day to the 28th day on adding chitosan to all the 4 types of GIC. Amongst those, type IX high-strength posterior extra with chitosan released a considerably higher quantity of fluoride at all time intervals.

conclusionsIn all the experimental groups, adding chitosan to the glass ionomer liquid had an accelerating effect on its fluoride-releasing property.

Indexed as

ChitosanFluoridesAcrylic ResinsGlass Ionomer CementsHumansMaterials TestingSilicon DioxideAcrylic ResinsChitosanFluoridesglass ionomerGlass Ionomer CementsSilicon DioxideCementChitosanFluoride releaseGlass ionomer cementModifiedNanoparticlesRestoration

Identifiers

PMID35810014
PMCPMC9676517
OpenAlexW4284664125

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.