Evidence map›Paper›PMID 35809825›Full record

Trial reportPreventive medicine2022

Childhood COVID-19 vaccine acceptance and preference from caregivers and healthcare workers in China: A survey experiment.

Zhiyuan Hou, Kuimeng Song, Qian Wang, Shujie Zang, Shiyi Tu, Tracey Chantler, Heidi J Larson

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Preventive medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhiyuan HouSchool of Public Health, NHC Key Laboratory of Health Technology Assessment, Fudan University, Shanghai, China. Electronic address: zyhou@fudan.edu.cn.
Kuimeng SongSchool of Health Care Security, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.
Qian WangSchool of Public Health, NHC Key Laboratory of Health Technology Assessment, Fudan University, Shanghai, China.
Shujie ZangSchool of Public Health, NHC Key Laboratory of Health Technology Assessment, Fudan University, Shanghai, China.
Shiyi TuSchool of Public Health, NHC Key Laboratory of Health Technology Assessment, Fudan University, Shanghai, China.
Tracey ChantlerDepartment of Global Health and Development, London School of Hygiene & Tropical Medicine, UK.
Heidi J LarsonDepartment of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, UK; Department of Health Metrics Sciences, University of Washington, Seattle, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With approval of more COVID-19 vaccines for children, vaccine attributes may influence parental acceptance and choices. We aimed to assess effects of vaccine attributes and information on herd immunity on childhood COVID-19 vaccine acceptance. A survey experiment was conducted with caregivers of children aged 6 months to 11 years old and health care workers (HCWs) in China from September 14 to November 18, 2021. Respondents were randomly assigned to receive differing information on herd immunity (> 80% of the entire population must be vaccinated; or no information). Respondents then completed eight discrete choice tasks to assess vaccine acceptance based on attributes. 2331 (90.07%) of 2588 surveyed caregivers and 1576 (92.71%) of 1700 surveyed HCWs would accept COVID-19 vaccination for children, respectively. High Odds Ratios (OR) were found for acceptance of a vaccine with 90% over 50% efficacy (OR 6.70 [95% CI 6.11-7.35] for caregivers; 11.44 [10.12-12.95] for HCWs); and risk of adverse reactions to be 1 over 10 in 10,000 (3.96 [3.72-4.22] for caregivers; 2.98 [2.76-3.22] for HCWs). To achieve herd immunity target (> 80% vaccination coverage), vaccine efficacy should reach over 70% and risk of adverse reactions lower than 1 in 10,000. Knowledge on herd immunity target increased the odds of vaccine acceptance (1.82 [1.34-2.46] for caregivers; 2.42 [1.58-3.72] for HCWs). Childhood COVID-19 vaccine acceptance was high in China, independent of child's age, and depended on vaccine attributes.

Indexed as

COVID-19COVID-19 VaccinesCaregiversChildChinaHealth PersonnelHumansSurveys and QuestionnairesVaccinationCOVID-19 VaccinesAcceptanceChildChinaCOVID-19 vaccineSurvey experiment

Identifiers

PMID35809825
PMCPMC9259187

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.