ArticleDiabetes research and clinical practice2022
Stress hyperglycemia ratio, rather than admission blood glucose, predicts in-hospital mortality and adverse outcomes in moderate-to severe COVID-19 patients, irrespective of pre-existing glycemic status.
Article in Diabetes research and clinical practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Association between stress hyperglycemia ratio and prognosis of patients hospitalized with COVID-19: A meta-analysis.Journal of diabetes investigation · 2026Pooled it
- Relationship between stress hyperglycaemic ratio (SHR) and critical illness: a systematic review.Cardiovascular diabetology · 2025Pooled it
- The association between the stress hyperglycaemia ratio and mortality in cardiovascular disease: a meta-analysis and systematic review.Cardiovascular diabetology · 2024Pooled it
- Risk phenotypes of diabetes and association with COVID-19 severity and death: an update of a living systematic review and meta-analysis.Diabetologia · 2023Pooled it
- Joint effects of triglyceride-glucose-BMI and stress hyperglycemia ratio on all-cause mortality in trauma surgical intensive care patients: a multicenter cohort study.Lipids in health and disease · 2026Article
- Stress hyperglycemia ratio improves machine learning-based mortality risk prediction in critically ill COVID-19 patients: a multicenter retrospective study.BMC infectious diseases · 2026Article
- Integrating Admission Hyperglycemia Into Multidisciplinary Risk Stratification for Sepsis in the ICU: A Retrospective Cohort Study.Journal of multidisciplinary healthcare · 2026Article
- Clinical Significance and Associations of Stress Hyperglycemia in Severe Fever with Thrombocytopenia Syndrome.Infection and drug resistance · 2026Article
- Benzydamine Attenuates Matrix Metalloproteinase-9 Expression Through Inhibition of ERK MAPK in Activated Human Monocytic Cells Under Hyperglycemic Condition.Mediators of inflammation · 2026Article
- Stress hyperglycemia ratio and mortality in critically ill patients with heart failure: a retrospective cohort study from the MIMIC-IV database.BMC cardiovascular disorders · 2025Article
- U-shaped association of the stress hyperglycemia ratio with all-cause mortality and premature death in patients with cardiovascular disease: a cohort study.Diabetology & metabolic syndrome · 2025Article
- Association between stress hyperglycaemia ratio and admission stroke severity: a retrospective study in a Chinese single-centre cohort.BMJ open · 2025Article
- The Role of Stress Hyperglycemia on Delirium Onset.Journal of clinical medicine · 2025Review
- Stress hyperglycemia ratio and risk of incident myocardial infarction in the general population: a large-scale cohort study.Frontiers in nutrition · 2025Article
- Is pulmonary vascular remodeling an intermediate link between hyperglycemia and adverse outcomes in patients with idiopathic pulmonary arterial hypertension? Insights from a multi-center cohort study.Cardiovascular diabetology · 2024Observational
- Stress hyperglycemia ratio and its influence on mortality in elderly patients with severe community-acquired pneumonia: a retrospective study.Aging clinical and experimental research · 2024Article
- Diabetes related phenotypes and their influence on outcomes of patients with corona virus disease 2019 (COVID-19).Diabetology & metabolic syndrome · 2023Article
- Stress hyperglycemia ratio is associated with systemic inflammation and clinical outcomes in diabetic inpatients with pneumonia on admission.Journal of diabetes · 2023Article
- Glycemic Dysregulation, Inflammation and Disease Outcomes in Patients Hospitalized with COVID-19: Beyond Diabetes and Obesity.Viruses · 2023Article
- Association of acute-to-chronic glycemic ratio and outcomes in patients with COVID-19 and undiagnosed diabetes mellitus: A retrospective nationwide cohort study.Journal of diabetes investigation · 2023Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo compare admission-blood-glucose (ABG) or stress-hyperglycemia-ratio (SHR) performs better in predicting mortality and worse outcomes in COVID-19 patients with (DM) and without known Type 2 Diabetes Mellitus (UDM).
methodsABG and SHR were tested for 451 patients with moderate-severe COVID-19 infection [DM = 216,47.9%; pre-diabetes = 48,10.6%, UDM = 187,41.4%],who were followed-up to look for in-hospital-mortality (primary outcome) and secondary outcomes (ICU stay or mechanical ventilation, hospital-acquired-sepsis and multiple organ dysfunction syndrome [MODS]). Those with and without SHR ≥ 1.14 were compared; logistic regression was done to identify predictors of outcomes, with subgroup analysis based on pre-existing DM status and COVID-19 severity.
resultsThose who died (n = 131) or developed ≥ 1 secondary outcomes (n = 218) had higher prevalence of SHR ≥ 1.14, ABG ≥ 180 mg/dl and higher median SHR (p
conclusionSHR better predicts mortality and adverse outcomes than ABG in patients with COVID-19, irrespective of pre-existing chronic glycemic status.
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