Evidence map›Paper›PMID 35809204›Full record

ArticleInternational urology and nephrology2023

Short-term outcomes after transplantation of deceased donor kidneys with acute kidney injury: a retrospective analysis of a multicenter cohort of marginal donor kidneys with post-explantation biopsies.

Florian G Scurt, Angela Ernst, Tamara Wassermann, Ben Hammoud, Peter R Mertens, Anke Schwarz, Jan U Becker, Christos Chatzikyrkou

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in International urology and nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Performance of Scores Predicting Adverse Outcomes in Procurement Kidney Biopsies From Deceased Donors With Organs of Lower-Than-Average Quality.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Florian G ScurtUniversity Clinic for Nephrology and Hypertension, Diabetology and Endocrinology, Medical Faculty, Otto-Von Guericke University Magdeburg, Magdeburg, Germany. florian.scurt@med.ovgu.de.ORCID http://orcid.org/0000-0001-6197-4720
Angela ErnstInstitute of Medical Statistics and Bioinformatics, University of Cologne, Cologne, Germany.
Tamara WassermannUniversity Clinic for Nephrology and Hypertension, Diabetology and Endocrinology, Medical Faculty, Otto-Von Guericke University Magdeburg, Magdeburg, Germany.
Ben HammoudUniversity Clinic for Nephrology and Hypertension, Diabetology and Endocrinology, Medical Faculty, Otto-Von Guericke University Magdeburg, Magdeburg, Germany.
Peter R MertensUniversity Clinic for Nephrology and Hypertension, Diabetology and Endocrinology, Medical Faculty, Otto-Von Guericke University Magdeburg, Magdeburg, Germany.
Anke SchwarzDepartment of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany.
Jan U BeckerInstitute of Pathology, University Hospital of Cologne, Cologne, Germany.
Christos ChatzikyrkouDepartment of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany. chatziky@gmx.de.
University Clinic for Nephrology and Hypertension, Diabetology and Endocrinology · DEMedizinische Hochschule Hannover · DEUniversity Hospital Cologne · DEUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeceased donor kidneys with acute kidney injury (AKI) are often discarded because of concerns about inferior transplant outcomes. A means of grading the quality of such kidneys is the performance of procurement biopsies.

methodsThis is a retrospective study of 221 brain death donors with marginal kidneys transplanted in 223 recipients in Germany. Marginal kidneys were defined as kidneys with procurement biopsies done exceptionally to assess suitability for transplantation in otherwise potentially discarded organs. The impact of deceased donor AKI on patient survival and death-censored graft survival at 1, 3 and 5 years and graft function at 1 and 3 years after transplantation was investigated.

resultsRecipients of kidneys with stage 3 AKI had a greater incidence of delayed graft function [DGF; OR

conclusionThe transplantation of deceased donor marginal kidneys with AKI confers a higher risk for DGF but is associated with acceptable graft and patient outcomes, which do not differ in comparison with marginal donor kidneys without AKI. Graft prognosis is especially poor if donor AKI and recipient DGF concur. Donor AKI was a risk factor independent of the histological lesions of procurement biopsies.

Indexed as

Acute Kidney InjuryKidney TransplantationTissue and Organ ProcurementBiopsyDelayed Graft FunctionGraft SurvivalHumansKidneyRetrospective StudiesTissue DonorsAcute kidney injuryDelayed graft functionEnd-stage kidney diseaseTransplantation

Identifiers

PMID35809204
PMCPMC9807548
OpenAlexW4284990757

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.