Evidence map›Paper›PMID 35809147›Full record

ArticleActa neurochirurgica2022

Anterior transtemporal endoscopic selective amygdalohippocampectomy: a virtual and cadaveric feasibility study.

Ruth Lau, Andreu Gabarros, Juan Martino, Alejandro Fernandez-Coello, Jose-Luis Sanmillan, Arnau Benet, Olivia Kola, Roberto Rodriguez-Rubio

Abstract read
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In one paragraph

Article in Acta neurochirurgica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Ruth LauSkull Base and Cerebrovascular Laboratory, University of California, San Francisco, CA, USA. ruth_lau_rodriguez@hotmail.com.ORCID 0000-0002-8640-2339
Andreu GabarrosDeparment of Neurological Surgery, L´Hospital de Llobregat, Bellvitge University Hospital, 08907, Barcelona, Spain.
Juan MartinoDepartment of Neurological Surgery, Hospital Universitario Marqués de Valdecilla and Fundación Instituto de Investigación Marqués de Valdecilla (IDIVAL), Avda. Valdecilla s/n, 39008, Santander, Cantabria, Spain.
Alejandro Fernandez-CoelloDeparment of Neurological Surgery, L´Hospital de Llobregat, Bellvitge University Hospital, 08907, Barcelona, Spain.
Jose-Luis SanmillanDeparment of Neurological Surgery, L´Hospital de Llobregat, Bellvitge University Hospital, 08907, Barcelona, Spain.
Arnau BenetSkull Base and Cerebrovascular Laboratory, University of California, San Francisco, CA, USA.
Olivia KolaSkull Base and Cerebrovascular Laboratory, University of California, San Francisco, CA, USA.
Roberto Rodriguez-RubioSkull Base and Cerebrovascular Laboratory, University of California, San Francisco, CA, USA.
Bellvitge University Hospital · ESUniversity of California, San Francisco · USBarrow Neurological Institute · USInstituto de Investigación Marqués de Valdecilla · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSelective amygdalohippocampectomy (SelAH) is one of the most common surgical treatments for mesial temporal sclerosis. Microsurgical approaches are associated with the risk of cognitive and visual deficits due to damage to the cortex and white matter (WM) pathways. Our objective is to test the feasibility of an endoscopic approach through the anterior middle temporal gyrus (aMTG) to perform a SelAH.

methodsVirtual simulation with MRI scans of ten patients (20 hemispheres) was used to identify the endoscopic trajectory through the aMTG. A cadaveric study was performed on 22 specimens using a temporal craniotomy. The anterior part of the temporal horn was accessed using a tubular retractor through the aMTG after performing a 1.5 cm corticectomy at 1.5 cm posterior to the temporal pole. Then, an endoscope was introduced. SeIAH was performed in each specimen. The specimens underwent neuronavigation-assisted endoscopic SeIAH to confirm our surgical trajectory. WM dissection using Klingler's technique was performed on five specimens to assess WM integrity.

resultsThis approach allowed the identification of collateral eminence, lateral ventricular sulcus, choroid plexus, inferior choroidal point, amygdala, hippocampus, and fimbria. SelAH was successfully performed on all specimens, and CT neuronavigation confirmed the planned trajectory. WM dissection confirmed the integrity of language pathways and optic radiations.

conclusionsEndoscopic SelAH through the aMTG can be successfully performed with a corticectomy of 15 mm, presenting a reduced risk of vascular injury and damage to WM pathways. This could potentially help to reduce cognitive and visual deficits associated with SelAH.

Indexed as

Epilepsy, Temporal LobeTemporal LobeAmygdalaCadaverFeasibility StudiesHippocampusHumansEndoscopic selective amygdalohippocampectomyLanguage pathwaysMesial temporal lobe sclerosisMeyer’s loopOptic radiationsWhite matter

Identifiers

PMID35809147
OpenAlexW4284990671

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.