Evidence map›Paper›PMID 35809048›Full record

ArticleGigaScience2022

Chromosome-level genome assembly of Plazaster borealis sheds light on the morphogenesis of multiarmed starfish and its regenerative capacity.

Yujung Lee, Bongsang Kim, Jaehoon Jung, Bomin Koh, So Yun Jhang, Chaeyoung Ban, Won-Jae Chi, Soonok Kim, Jaewoong Yu

Open access · goldAbstract read
In one paragraph

Article in GigaScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yujung LeeDepartment of Research, eGnome, Inc., 26 Beobwon-ro 9-gil, Sonpa-gu, Seoul 05836, Republic of Korea.ORCID 0000-0003-2279-3147
Bongsang KimDepartment of Research, eGnome, Inc., 26 Beobwon-ro 9-gil, Sonpa-gu, Seoul 05836, Republic of Korea.ORCID 0000-0001-7526-8421
Jaehoon JungDepartment of Research, eGnome, Inc., 26 Beobwon-ro 9-gil, Sonpa-gu, Seoul 05836, Republic of Korea.ORCID 0000-0003-2019-0895
Bomin KohDepartment of Research, eGnome, Inc., 26 Beobwon-ro 9-gil, Sonpa-gu, Seoul 05836, Republic of Korea.ORCID 0000-0001-6702-6449
So Yun JhangDepartment of Research, eGnome, Inc., 26 Beobwon-ro 9-gil, Sonpa-gu, Seoul 05836, Republic of Korea.ORCID 0000-0002-2152-3746
Chaeyoung BanDepartment of Research, eGnome, Inc., 26 Beobwon-ro 9-gil, Sonpa-gu, Seoul 05836, Republic of Korea.ORCID 0000-0003-4566-4313
Won-Jae ChiDepartment of Microorganism Resources Division, National Institute of Biological Resources, Incheon 22689, Republic of Korea.ORCID 0000-0003-2893-7930
Soonok KimDepartment of Microorganism Resources Division, National Institute of Biological Resources, Incheon 22689, Republic of Korea.ORCID 0000-0003-1654-3643
Jaewoong YuDepartment of Research, eGnome, Inc., 26 Beobwon-ro 9-gil, Sonpa-gu, Seoul 05836, Republic of Korea.ORCID 0000-0002-4120-8890
Suwon Research Institute · KRSeoul National University · KRNational Institute of Biological Resources · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPlazaster borealis has a unique morphology, displaying multiple arms with a clear distinction between disk and arms, rather than displaying pentaradial symmetry, a remarkable characteristic of echinoderms. Herein we report the first chromosome-level reference genome of P. borealis and an essential tool to further investigate the basis of the divergent morphology.

findingsIn total, 57.76 Gb of a long read and 70.83 Gb of short-read data were generated to assemble a de novo 561-Mb reference genome of P. borealis, and Hi-C sequencing data (57.47 Gb) were used for scaffolding into 22 chromosomal scaffolds comprising 92.38% of the genome. The genome completeness estimated by BUSCO was 98.0% using the metazoan set, indicating a high-quality assembly. Through the comparative genome analysis, we identified evolutionary accelerated genes known to be involved in morphogenesis and regeneration, suggesting their potential role in shaping body pattern and capacity of regeneration.

conclusionThis first chromosome-level genome assembly of P. borealis provides fundamental insights into echinoderm biology, as well as the genomic mechanism underlying its unique morphology and regeneration.

Indexed as

ChromosomesStarfishAnimalsGenomeGenomicsMorphogenesisgenome assemblyHi-CNanoporePlazaster borealis

Identifiers

PMID35809048
PMCPMC9270726
OpenAlexW4284988320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.