Evidence map›Paper›PMID 35808977›Full record

ArticleJournal of anatomy2022

Characterisation of the consequences of maternal immune activation on distinct cell populations in the developing rat spinal cord.

Rebecca C Anderson, Gerard W O'Keeffe, Kieran W McDermott

Open access · hybridAbstract read
In one paragraph

Article in Journal of anatomy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Rebecca C AndersonSchool of Medicine, University of Limerick, Limerick, Ireland.
Gerard W O'KeeffeDepartment of Anatomy and Neuroscience, University College Cork, Cork, Ireland.
Kieran W McDermottSchool of Medicine, University of Limerick, Limerick, Ireland.ORCID 0000-0002-3287-8649
University of Limerick · IEUniversity College Cork · IE

Funding

Anatomical SocietyUniversity of Limerick
6 · The paper itself

Abstract

Maternal immune activation (MIA) during gestation has been implicated in the development of neurological disorders such as schizophrenia and autism. Epidemiological studies have suggested that the effect of MIA may depend on the gestational timing of the immune challenge and the region of the central nervous system (CNS) in question. This study investigated the effects of MIA with 100 μg/kg lipopolysaccharide at either Embryonic days (E)12 or E16 on the oligodendrocytes, microglia and astrocytes of the offspring spinal cord. At E16, MIA decreased the number of olig2

Indexed as

LipopolysaccharidesSpinal CordAnimalsAstrocytesGlial Fibrillary Acidic ProteinMicrogliaRatsGlial Fibrillary Acidic ProteinLipopolysaccharidesastrogliacellular developmentdevelopmentmaternal immune activationmaternal infectionmicroglianeurodevelopmentoligodendrocytesspinal cord

Identifiers

PMID35808977
PMCPMC9482694
OpenAlexW4284971572

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.