Evidence map›Paper›PMID 35808939›Full record

ArticleContact dermatitis2022

A comparison between self-reported hand eczema and self-reported signs and symptoms of skin lesions indicating hand eczema.

Yasemin Topal Yüksel, Jacob P Thyssen, Line Brok Nørreslet, Esben Meulengracht Flachs, Niels Erik Ebbehøj, Tove Agner

Open access · hybridAbstract read
In one paragraph

Article in Contact dermatitis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yasemin Topal YükselDepartment of Dermatology, Bispebjerg & Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0003-1289-1827
Jacob P ThyssenDepartment of Dermatology, Bispebjerg & Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0003-3770-1743
Line Brok NørresletDepartment of Dermatology, Bispebjerg & Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-3702-1409
Esben Meulengracht FlachsDepartment of Occupational and Environmental Medicine, Bispebjerg & Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark.
Niels Erik EbbehøjDepartment of Occupational and Environmental Medicine, Bispebjerg & Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark.
Tove AgnerDepartment of Dermatology, Bispebjerg & Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-7543-8299
University of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe accuracy of self-reported hand eczema (HE) is currently unclear, and it is unknown how well self-reported signs and symptoms of skin lesions that indicate HE correlate with self-reported HE.

objectivesTo correlate self-reported signs and symptoms of skin lesions on the hands with self-reported HE, to assess the sensitivity and specificity, and to suggest a definition for HE.

methodSeven hundred ninety-five (47.8%) of 1663 invited healthcare workers completed a digital questionnaire, and were asked to report if they experienced HE or any of the following skin signs/symptoms in past 11 months: scaling, erythema, fissures, vesicles, dryness, itch, stinging.

resultsHE during the past 11 months was reported by 11.9%. Of these, 91.4% reported at least one skin sign versus 32.3% of those without self-reported HE. The highest sensitivity and specificity were found for erythema (77.4% and 78.2%, respectively) and itch (78.5% and 78.6%, respectively), both separately and combined. The combination of ≥2 signs (erythema, scaling, fissures and vesicles) and itch, reached a sensitivity of 52.7% and specificity of 93.9%.

conclusionThe marked difference between self-reported HE and signs/symptoms highlights the importance of differentiating between data based on self-reported HE and signs/symptoms. As a first step towards diagnostic HE criteria, ≥2 signs combined with itch could be considered, but clinical studies are needed to verify the precision.

Indexed as

Dermatitis, Allergic ContactEczemaHand DermatosesHumansPruritusSelf ReportSkindiagnostic criteriaepidemiologyhand eczemaself-reports

Identifiers

PMID35808939
PMCPMC9796092
OpenAlexW4284964330

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.