Evidence map›Paper›PMID 35808890›Full record

ArticleJournal of clinical laboratory analysis2022

RLLB/Alb ratio: a promising noninvasive diagnostic marker in assessing esophageal varices in cirrhotic patients.

Md Faisal Fahad Chowdhury, Ashekul Islam, Pulak Kanti Palit, Md Mozibullah, Md Sohel, Mst Mahmuda Khatun, Mohammed Mehadi Hassan Chowdhury, Mohammod Johirul Islam, Joyonti Datta, Suman Dhar and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical laboratory analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Md Faisal Fahad ChowdhuryDepartment of Gastroenterology, Chittagong Medical College Hospital, Chattogram, Bangladesh.
Ashekul IslamDepartment of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Tangail, Bangladesh.ORCID https://orcid.org/0000-0003-3395-0320
Pulak Kanti PalitDepartment of Medicine, Chittagong Medical College, Chattogram, Bangladesh.
Md MozibullahDepartment of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Tangail, Bangladesh.
Md SohelDepartment of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Tangail, Bangladesh.
Mst Mahmuda KhatunDepartment of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Tangail, Bangladesh.
Mohammed Mehadi Hassan ChowdhuryDepartment of Microbiology, Noakhali Science and Technology University, Noakhali, Bangladesh.
Mohammod Johirul IslamDepartment of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University, Tangail, Bangladesh.
Joyonti DattaDepartment of Medicine, Chittagong Medical College, Chattogram, Bangladesh.
Suman DharDepartment of Medicine, Chittagong Medical College, Chattogram, Bangladesh.
Pradip Kumar NathDepartment of Medicine, Chittagong Medical College, Chattogram, Bangladesh.
Sabuj Kanti NathDepartment of Medicine, Chittagong Medical College, Chattogram, Bangladesh.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndoscopy has long been widely used to screen for esophageal varices (EV) in cirrhotic patients. Recurrent endoscopy is a significant burden for the healthcare system of the endoscopic unit as well as uncomfortable and high costs for patients. This study intended to prognosticate Right Liver Lobe Diameter/Serum Albumin Ratio (RLLD/Alb) as a non-invasive approach in the early diagnosis of EV among chronic liver disease (CLD) Bangladeshi patients enrolled in a specific hospital. PARTICIPANTS AND

methodsA total of 150 admitted patients with CLD were included in the study. Patients were subjected through a comprehensive biochemical checkup and upper digestive endoscopic or ultrasonographic inspection. The correlation was evaluated between the RLLD/Alb ratio and esophageal varices grades.

resultsThe upper digestive endoscopy demonstration among 150 patients resulted in no EV in 18%, while 24% of patients was identified as EV grade I, 20% as grade II, 20% as grade III, and 18% patients as grade IV. The mean value of the RLLD/Alb ratio was 4.89 ± 1.49 (range from 2.30 to 8.45). The RLLD/Alb ratio diagnosed the EV employing the cut-off value of 4.01 with 85.3% sensitivity and 68.8% specificity. Furthermore, it was positively correlated with the grading of EV, when this ratio increased the grading of EV increases and vice versa (r = 0.630, p < 0.001).

conclusionThe RLLD/Alb ratio is a non-invasive parameter giving exact guidance relevant to the ascertainment of the existence of EV and their grading in chronic liver disease patients.

Indexed as

Esophageal and Gastric VaricesEndoscopy, GastrointestinalHumansLiverLiver CirrhosisSerum AlbuminSerum Albuminesophageal varices (EV)liver cirrhosisright liver lobe diameter/serum albumin ratioultrasonographyupper digestive endoscopy

Identifiers

PMID35808890
PMCPMC9396198

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.