Evidence map›Paper›PMID 35808798›Full record

ReviewPolymers2022

An Overview of In Vitro Drug Release Methods for Drug-Eluting Stents.

Navideh Abbasnezhad, Nader Zirak, Stéphane Champmartin, Mohammadali Shirinbayan, Farid Bakir

Abstract readReview
In one paragraph

Review in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Coatings for Cardiovascular Stents-An Up-to-Date Review.International journal of molecular sciences · 2024
    Review
  6. Article
  7. Engineering In Situ Weldable Vascular Devices.Bioengineering (Basel, Switzerland) · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Navideh AbbasnezhadArts et Métiers Institute of Technology, CNAM, LIFSE, HESAM University, F-75013 Paris, France.ORCID 0000-0001-6217-8267
Nader ZirakArts et Métiers Institute of Technology, CNAM, LIFSE, HESAM University, F-75013 Paris, France.
Stéphane ChampmartinArts et Métiers Institute of Technology, CNAM, LIFSE, HESAM University, F-75013 Paris, France.
Mohammadali ShirinbayanArts et Métiers Institute of Technology, CNAM, PIMM, HESAM University, F-75013 Paris, France.ORCID 0000-0002-2757-8529
Farid BakirArts et Métiers Institute of Technology, CNAM, LIFSE, HESAM University, F-75013 Paris, France.ORCID 0000-0003-0837-0260

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The drug release profile of drug-eluting stents (DESs) is affected by a number of factors, including the formulation, design, and physicochemical properties of the utilized material. DES has been around for twenty years and despite its widespread clinical use, and efficacy in lowering the rate of target lesion restenosis, it still requires additional development to reduce side effects and provide long-term clinical stability. Unfortunately, for analyzing these implants, there is still no globally accepted in vitro test method. This is owing to the stent's complexity as well as the dynamic arterial compartments of the blood and vascular wall. The former is the source of numerous biological, chemical, and physical mechanisms that are more commonly observed in tissue, lumen, and DES. As a result, universalizing bio-relevant apparatus, suitable for liberation testing of such complex implants is difficult. This article aims to provide a comprehensive review of the methods used for in vitro release testing of DESs. Aspects related to the correlation of the release profiles in the cases of in vitro and in vivo are also addressed.

Indexed as

drug-eluting stentsflow conditionshydrogelsin vitro release testingIVIV correlation

Identifiers

PMID35808798
PMCPMC9269075

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.