Evidence map›Paper›PMID 35808077›Full record

ReviewNanomaterials (Basel, Switzerland)2022

Progress, Opportunities, and Challenges of Magneto-Plasmonic Nanoparticles under Remote Magnetic and Light Stimulation for Brain-Tissue and Cellular Regeneration.

Muzhaozi Yuan, Mackenzie Caitlin Harnett, Tian-Hao Yan, Elias Georgas, Yi-Xian Qin, Hong-Cai Zhou, Ya Wang

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Muzhaozi YuanJ. Mike Walker '66 Department of Mechanical Engineering, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0001-5542-065X
Mackenzie Caitlin HarnettJ. Mike Walker '66 Department of Mechanical Engineering, Texas A&M University, College Station, TX 77843, USA.
Tian-Hao YanDepartment of Chemistry, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0002-8900-3720
Elias GeorgasDepartment of Biomedical Engineering, State University of New York, Stony Brook, NY 11794-5281, USA.ORCID 0000-0001-6538-9641
Yi-Xian QinDepartment of Biomedical Engineering, State University of New York, Stony Brook, NY 11794-5281, USA.
Hong-Cai ZhouDepartment of Chemistry, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0002-9029-3788
Ya WangJ. Mike Walker '66 Department of Mechanical Engineering, Texas A&M University, College Station, TX 77843, USA.

Funding

National Science Foundation 1751435National Science Foundation 2020867National Science Foundation 2021081
6 · The paper itself

Abstract

Finding curable therapies for neurodegenerative disease (ND) is still a worldwide medical and clinical challenge. Recently, investigations have been made into the development of novel therapeutic techniques, and examples include the remote stimulation of nanocarriers to deliver neuroprotective drugs, genes, growth factors, and antibodies using a magnetic field and/or low-power lights. Among these potential nanocarriers, magneto-plasmonic nanoparticles possess obvious advantages, such as the functional restoration of ND models, due to their unique nanostructure and physiochemical properties. In this review, we provide an overview of the latest advances in magneto-plasmonic nanoparticles, and the associated therapeutic approaches to repair and restore brain tissues. We have reviewed their potential as smart nanocarriers, including their unique responsivity under remote magnetic and light stimulation for the controlled and sustained drug delivery for reversing neurodegenerations, as well as the utilization of brain organoids in studying the interaction between NPs and neuronal tissue. This review aims to provide a comprehensive summary of the current progress, opportunities, and challenges of using these smart nanocarriers for programmable therapeutics to treat ND, and predict the mechanism and future directions.

Indexed as

brain organoidcontrolled and sustained drug releaselight stimulationmagnetic fieldmagneto-plasmonic nanoparticlesneurodegenerative disease

Identifiers

PMID35808077
PMCPMC9268050

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.