Evidence map›Paper›PMID 35807888›Full record

Trial reportNutrients2022

IQ Was Not Improved by Post-Discharge Fortification of Breastmilk in Very Preterm Infants.

Anja Klamer, Line H Toftlund, Kristjan Grimsson, Susanne Halken, Gitte Zachariassen

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. [Research hotspots in post-discharge follow-up management of preterm infants].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Anja KlamerHans Christian Andersen Children's Hospital, Odense University Hospital, 5000 Odense, Denmark.
Line H ToftlundDepartment of Paediatrics, Holbaek Hospital, 4300 Holbaek, Denmark.
Kristjan GrimssonHans Christian Andersen Children's Hospital, Odense University Hospital, 5000 Odense, Denmark.
Susanne HalkenHans Christian Andersen Children's Hospital, Odense University Hospital, 5000 Odense, Denmark.
Gitte ZachariassenHans Christian Andersen Children's Hospital, Odense University Hospital, 5000 Odense, Denmark.
Odense University Hospital · DKHolbæk Sygehus · DKUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Very preterm infants are at increased risk of cognitive deficits, motor impairments, and behavioural problems. Studies have tied insufficient nutrition and growth to an increased risk of neurodevelopmental impairment; (2) Methods: Follow-up study on cognitive and neuropsychological development at 6 years corrected age (CA) in 214 very preterm infants, including 141 breastfed infants randomised to mother's own milk (MOM) with (F-MOM) or without (U-MOM) fortification and 73 infants fed a preterm formula (PF-group), from shortly before discharge to 4 months CA. Infants with serious congenital anomalies or major neonatal morbidities were excluded prior to intervention. The Wechsler Intelligence Scale for Children IV was used for cognitive testing, and the children's parents completed the Five to Fifteen Questionnaire (FTF); (3) Results: Post-discharge fortification of MOM did not improve either full-scale intelligence quotient (FSIQ) with a median of 104 vs. 105.5 (

Indexed as

Infant, Premature, DiseasesMilk, HumanAftercareBreast FeedingChildFemaleFetal Growth RetardationFollow-Up StudiesHumansInfantInfant, NewbornInfant, PrematurePatient Dischargebreastfeedingcognitive developmentFive to Fifteen Questionnairefortificationpost-discharge nutritionpreterm infantWechsler Intelligence Scale for Children IV

Identifiers

PMID35807888
PMCPMC9268839
OpenAlexW4283718681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.