ArticleNutrients2022
Association between Selenium Status and Chronic Kidney Disease in Middle-Aged and Older Chinese Based on CHNS Data.
Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Pooled it
- Joint and Independent Associations of Dietary Antioxidant Intakes With Advanced Stages in Older Patients With Cardiovascular-Kidney-Metabolic Syndrome.The Kaohsiung journal of medical sciences · 2026Article
- Dietary trace mineral intake and risk of all-cause and cardiovascular mortality in population with cardiovascular-kidney-metabolic syndrome stage 0-3: a cohort study.BMC public health · 2026Article
- Heavy metal exposure and risk of all-cause and cardiovascular mortality in population with cardiovascular-kidney-metabolic syndrome stage 0-3: a cohort study.Environmental health and preventive medicine · 2026Article
- Protic small molecule bioregulators.Redox biology · 2025Review
- Evaluating the impact of environmental metal mixtures on chronic kidney disease risk: Insights from the National Health and Nutrition Examination Survey 2011-2016.The Journal of international medical research · 2025Article
- Unhealthy diet and lifestyle factors linked to female androgenetic alopecia: a community-based study from Jidong study, China.BMC public health · 2025Article
- Association of composite dietary antioxidant index with mortality risk among adults with chronic kidney disease in NHANES.Scientific reports · 2025Article
- Association of multiple dietary metal intake with cardiovascular-kidney-metabolic syndrome: a cross-sectional study based on NHANES 2003-2018.Frontiers in nutrition · 2025Article
- Crosstalk between ferroptosis and innate immune in diabetic kidney disease: mechanisms and therapeutic implications.Frontiers in immunology · 2025Review
- Comprehensive Insights into the Health Effects of Selenium Exposure and Supplementation Among the Chinese Community Middle-Aged and Elderly: a Combined Retrospective Cohort Study and Intervention Study.Biological trace element research · 2024Article
- Role of Nutrients in Pediatric Non-Dialysis Chronic Kidney Disease: From Pathogenesis to Correct Supplementation.Biomedicines · 2024Review
- Preoperative serum selenium predicts acute kidney injury after adult cardiac surgery.BMC cardiovascular disorders · 2024Article
- Uric acid mediates the relationship between mixed heavy metal exposure and renal function in older adult people.Frontiers in public health · 2024Article
- Comparative mathematical modeling of causal association between metal exposure and development of chronic kidney disease.Frontiers in endocrinology · 2024Article
- Association between dietary intake of selenium and chronic kidney disease in US adults: a cross-sectional study of NHANES 2015-2018.Frontiers in nutrition · 2024Article
- Mendelian randomization analyses explore the effects of micronutrients on different kidney diseases.Frontiers in nutrition · 2024Article
- Article
- Higher Levels of Blood Selenium are Associated with Higher Levels of Serum Lipid Profile in US Adults with CKD: Results from NHANES 2013-2018.Biological trace element research · 2023Article
- Further Evidence on Trace Element Imbalances in Haemodialysis Patients-Paired Analysis of Blood and Serum Samples.Nutrients · 2023Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundThe association between selenium and chronic kidney disease (CKD) remains controversial. Population studies with large samples facilitate the reliability of conclusions.
objectiveIn this study, we aimed to describe the prevalence of a CKD association with selenium intake in middle-aged and older Chinese.
methodsData for this study were obtained from the China Health and Nutrition Survey (CHNS). A total of 5381 participants (aged ≥ 45) with biochemical test data were included in the study. Logistic regression models were used to examine the association between diet selenium intake (quartile) and the prevalence of CKD.
resultsA total of 942 (17.01%) participants had CKD. The prevalence of CKD was 23.33%, 20.32%, 14.98%, and 9.25% among participants with average selenium intakes of 21.5 ± 4.82, 33.1 ± 2.79, 43.8 ± 3.70, and 67.0 ± 13.97 µg/day, respectively. In the fully adjusted model (Model 3), across the quartiles of selenium intake, the ORs for the prevalence of CKD were 1.00, 1.09 (95% CI 0.69-1.73), 0.82 (95% CI 0.49-1.38), and 0.43 (95% CI 0.22-0.85). The protein intake had a certain diagnostic significance for the selenium intake.
conclusionsAn adequate selenium intake may have a positive effect on CKD. The influence of individual weight and location on the effect of selenium on CKD needs to be further explored.
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