ArticleNutrients2022
Blood Chromium Levels and Their Association with Cardiovascular Diseases, Diabetes, and Depression: National Health and Nutrition Examination Survey (NHANES) 2015-2016.
Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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25 citing papers in PubMed, 49 citations in OpenAlex.
- The Effect of Serum Trace Element Levels On Cardiovascular Diseases in Adults in the Ravansar Region (Western Iran): A Risk Assessment Study in the Context of Elevated Lipid Profiles.Cardiovascular toxicology · 2026Article
- Association between essential trace elements, dietary patterns, and biological aging.European journal of nutrition · 2026Article
- The mediating role of vascular age in the association between blood metals and atherosclerosis from Manganese-exposed workers healthy cohort.BMC public health · 2026Article
- Essential and Toxic Elements in Cardiovascular Disease: Pathophysiological Roles and the Emerging Contribution of Hair Mineral Analysis.International journal of molecular sciences · 2025Review
- Assessment of trace element imbalances in diabetes mellitus patients with and without diabetic retinopathy: a case-control study in Iraq.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- Impact of zinc and chromium deficiency on gene expression in type 2 diabetes mellitus.Scientific reports · 2025Article
- A prospective study of a whole blood metal mixture and depressive symptoms among Black women from Detroit, Michigan.Neurotoxicology · 2025Article
- Antidepressant use and all-cause mortality in depressed individuals: A real-world cohort study.PloS one · 2025Article
- The independent and combined effects of blood heavy metal concentrations on all-cause mortality and cardiovascular mortality in adult patients with diabetes mellitus.Frontiers in public health · 2025Article
- Editorial: Omics in endocrinology: from biomarker discovery to targeting therapeutic strategies.Frontiers in molecular biosciences · 2025Article
- Association Between Serum Concentrations of (Certain) Metals and Type 2 Diabetes Mellitus.Journal of clinical medicine · 2024Review
- Butterfly-Inspired Multiple Cross-Linked Dopamine-Metal-Phenol Bioprosthetic Valves with Enhanced Endothelialization and Anticalcification.ACS applied materials & interfaces · 2024Article
- Effect of Whole Blood Dietary Mineral Concentrations on Erythrocytes: Selenium, Manganese, and Chromium: NHANES Data.Nutrients · 2024Article
- Associations of ethylene oxide exposure with depression in American adults.Scientific reports · 2024Article
- Effects of PMEnvironment & health (Washington, D.C.) · 2024Article
- The association between the urinary chromium and blood pressure: a population-based study.BMC cardiovascular disorders · 2024Article
- The relationship between BMI and depression: a cross-sectional study.Frontiers in psychiatry · 2024Article
- Study on the metabolic effects of hexavalent chromium [Cr (VI)] on rat astrocytes using un-targeted metabolomics.Frontiers in molecular biosciences · 2024Article
- Higher serum chromium level may be associated with the presentation of depression in patients with metabolic dysfunction-associated fatty liver disease: evidence from NHANES survey.Frontiers in psychiatry · 2024Article
- Chromium Supplementation to Reduce Cardiometabolic Risk Factors: A Novel Dose-Response Meta-Analysis of Randomized Clinical Trials.JACC. Advances · 2023Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Currently, there is no global consensus about the essentiality of dietary chromium. To provide evidence to this debate, an examination of blood chromium levels and common chronic health conditions was undertaken. Using a subsample from the 2015−2016 US National Health and Nutrition Examination Survey (n = 2894; 40 years+), chi-square and binary logistic regression analyses were conducted to examine blood chromium levels (0.7−28.0 vs. <0.7 µg/L) and their associations with cardiovascular diseases (CVDs; self-report), diabetes mellitus (DM; glycohemoglobin ≥5.7%), and depression (Patient Health Questionnaire-9 score ≥5), while controlling for socio-demographic (age/sex/income/education/relationship status) and health-related (red blood cell folate/medications/co-morbidities/body mass index (BMI)/substance use) factors. The sample was almost evenly distributed between men and women (n = 1391, 48.1% (men); n = 1503, 51.9% (women)). The prevalence estimates of low blood chromium levels tended to be higher among those with CVDs (47.4−47.6%) and DM (50.0−51.6%). Comparisons between those with low vs. normal blood chromium levels indicate men have increased odds of CVDs (adjusted odds ratio (aOR) = 1.86, 95% confidence interval (CI): 1.22−2.85, p < 0.001) and DM (aOR = 1.93, 95% CI: 1.32−2.83, p < 0.001) and lower odds of depression (aOR = 0.42, 95% CI: 0.22−0.77, p < 0.05). Dietary chromium may be important in the prevention and management of CVDs and DM for men. Continued exploration of chromium’s role in chronic diseases, including differences by biological factors, is needed.
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