Evidence map›Paper›PMID 35807837›Full record

ArticleNutrients2022

Pollen Food Allergy Syndrome in Allergic March.

Hiroki Yasudo, Kiwako Yamamoto-Hanada, Limin Yang, Mayako Saito-Abe, Miori Sato, Yumiko Miyaji, Mami Shimada, Seiko Hirai, Kenji Toyokuni, Fumi Ishikawa and 4 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Pollen-Food Allergy Syndrome in China: Current Knowledge and Future Research Needs.International archives of allergy and immunology · 2026
    Review
  2. Prevalence and sensitization of pollen-food allergy syndrome among adolescents in Tokyo.The journal of allergy and clinical immunology. Global · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Hiroki YasudoAllergy Center, National Center for Child Health and Development, Tokyo 157-8535, Japan.
Kiwako Yamamoto-HanadaAllergy Center, National Center for Child Health and Development, Tokyo 157-8535, Japan.ORCID 0000-0003-1288-9620
Limin YangAllergy Center, National Center for Child Health and Development, Tokyo 157-8535, Japan.ORCID 0000-0002-3936-6371
Mayako Saito-AbeAllergy Center, National Center for Child Health and Development, Tokyo 157-8535, Japan.
Miori SatoAllergy Center, National Center for Child Health and Development, Tokyo 157-8535, Japan.
Yumiko MiyajiAllergy Center, National Center for Child Health and Development, Tokyo 157-8535, Japan.
Mami ShimadaAllergy Center, National Center for Child Health and Development, Tokyo 157-8535, Japan.
Seiko HiraiAllergy Center, National Center for Child Health and Development, Tokyo 157-8535, Japan.
Kenji ToyokuniAllergy Center, National Center for Child Health and Development, Tokyo 157-8535, Japan.
Fumi IshikawaAllergy Center, National Center for Child Health and Development, Tokyo 157-8535, Japan.
Yusuke InuzukaAllergy Center, National Center for Child Health and Development, Tokyo 157-8535, Japan.
Shigenori KabashimaAllergy Center, National Center for Child Health and Development, Tokyo 157-8535, Japan.
Tatsuki FukuieAllergy Center, National Center for Child Health and Development, Tokyo 157-8535, Japan.ORCID 0000-0003-4962-2137
Yukihiro OhyaAllergy Center, National Center for Child Health and Development, Tokyo 157-8535, Japan.ORCID 0000-0002-1560-3942
National Center For Child Health and Development · JP

Funding

National Center For Child Health and Development 26-1
6 · The paper itself

Abstract

The association between pollen food allergy syndrome (PFAS) and allergic march remains unclear. In this prospective cohort study of the general population in Tokyo (T-Child Study), we found that sensitization to Cry j 1 and Fel d 1 at ages 5 and 9 years was associated with an increased risk of PFAS at 13 years old (at 5 years, Cry j 1: adjusted odds ratio aOR, 2.74; 95% confidence interval CI, 1.53-4.91; Fel d 1: aOR, 2.61; 95% CI, 1.31-5.19; at 9 years, Cry j 1: adjusted odds ratio aOR, 4.28; 95% confidence interval CI, 1.98-9.25; Fel d 1: aOR, 2.40; 95% CI, 1.33-4.32). In particular, sensitization to Bet v 1 at ages 5 and 9 years was associated with a strong risk of PFAS at the age of 13 years (at 5 years: aOR, 10.6; 95% CI, 2.64-42.5; at 9 years: aOR, 9.1; 95% CI, 4.71-17.6). PFAS risk by age 13 years was increased by any allergic symptom at 5 or 9 years, a combination of wheezing, eczema, and rhinitis, and Bet v 1 sensitization. Our findings suggest that PFAS may be associated with allergic march.

Indexed as

FluorocarbonsFood HypersensitivityAdolescentAllergensChildChild, PreschoolHumansPollenProspective StudiesSyndromeAllergensFluorocarbonsallergic (atopic) marchBet v 1Cry j 1pollen food allergy syndromesensitization

Identifiers

PMID35807837
PMCPMC9268136
OpenAlexW4283646289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.