Evidence map›Paper›PMID 35807824›Full record

ArticleNutrients2022

Association between Dietary Anthocyanidins and Risk of Lung Cancer.

Yin Zhang, Min Zhu, Huajing Wan, Ling Chen, Fengming Luo

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yin ZhangDepartment of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Min ZhuDepartment of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Huajing WanDepartment of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Ling ChenDepartment of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Fengming LuoDepartment of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0000-0001-9267-3437
Sichuan University · CN

Funding

National Natural Science Foundation of China No.32070764; No.81800087
6 · The paper itself

Abstract

Background: Anthocyanidins are a kind of water-soluble flavonoids widely found in flowers and fruits of many plants. Although the beneficial effect of anthocyanidins in cancer prevention has been discussed, the value of anthocyanidins in lung cancer prevention requires further investigation. In this study, we aimed to explore the role of dietary anthocyanidins in the prevention of lung cancer in population-based prospective studies. Methods: Data of participants in this study were collected from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated in Cox proportional hazards regression for the association of dietary anthocyanidins and lung cancer risk. The dose-response relationship was explored between total anthocyanidins and the incidence of lung cancer. Results: A total of 97,993 participants were included in this study. The calculated HRs showed a trend that a higher quartile of total anthocyanidins indicated lower risk of lung cancer after adjusting for covariates (HRQ4vsQ1: 0.63; 95% CI: 0.55,0.73; p for trend < 0.001). A non-linear association between total anthocyanidins and lung cancer risk was found in the restricted cubic spline model. Conclusion: A protective association between dietary anthocyanidins and risk of lung cancer in Americans was investigated.

Indexed as

AnthocyaninsLung NeoplasmsDietFemaleHumansMaleProportional Hazards ModelsProspective StudiesRisk FactorsUnited StatesAnthocyaninsanthocyanidinsdose-response analysislung cancer

Identifiers

PMID35807824
PMCPMC9268346
OpenAlexW4283582738

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.