Evidence map›Paper›PMID 35807746›Full record

ArticleNutrients2022

Vitamin D and Risk of Obesity-Related Cancers: Results from the SUN ('Seguimiento Universidad de Navarra') Project.

Rodrigo Sánchez-Bayona, Maira Bes-Rastrollo, Cesar I Fernández-Lázaro, Maite Bastyr, Ainhoa Madariaga, Juan J Pons, Miguel A Martínez-González, Estefanía Toledo

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Rodrigo Sánchez-BayonaMedical Oncology Department, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.ORCID 0000-0002-5255-6620
Maira Bes-RastrolloDepartment of Preventive Medicine and Public Health, School of Medicine, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-9139-4206
Cesar I Fernández-LázaroDepartment of Preventive Medicine and Public Health, School of Medicine, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0003-2366-2528
Maite BastyrDepartment of Preventive Medicine and Public Health, School of Medicine, University of Navarra, 31008 Pamplona, Spain.
Ainhoa MadariagaMedical Oncology Department, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.ORCID 0000-0001-7166-9762
Juan J PonsIdiSNA, Navarra Institute for Health Research, 31008 Pamplona, Spain.ORCID 0000-0002-5623-1591
Miguel A Martínez-GonzálezDepartment of Preventive Medicine and Public Health, School of Medicine, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-3917-9808
Estefanía ToledoDepartment of Preventive Medicine and Public Health, School of Medicine, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-6263-4434
Navarre Institute of Health Research · ESHospital Universitario 12 De Octubre · ESUniversidad de Navarra · ES

Funding

Comunidad Foral de Navarra 27/2011, 45/2011, 122/2014European Regional Development Fund (FEDER) RD 06/0045Instituto de Salud Carlos III PI10/02658, PI10/02293, PI13/00615, PI14/01668, PI14/01798, PI14/01764, PI17/01795, PI20/00564
6 · The paper itself

Abstract

Obesity is associated with a higher risk of several types of cancer, grouped as obesity-related cancers (ORC). Vitamin D deficiency is more prevalent in obese subjects, and it has been suggested to play a role in the association between obesity and cancer risk. The aim of the study was to analyze the association between vitamin D intake and the subsequent risk of ORC in a prospective Spanish cohort of university graduates. The SUN Project, initiated in 1999, is a prospective dynamic multipurpose cohort. Participants answered a 556-item lifestyle baseline questionnaire that included a validated food-frequency questionnaire. We performed Cox regression models to estimate the hazard ratios (HRs) of ORC according to quartiles of energy-adjusted vitamin D intake (diet and supplements). We included 18,017 participants (mean age = 38 years, SD = 12 years), with a median follow-up of 12 years. Among 206,783 person-years of follow-up, we identified 225 cases of ORC. We found no significant associations between vitamin D intake and ORC risk after adjusting for potential confounders: HR

Indexed as

NeoplasmsVitamin DAdultCohort StudiesFollow-Up StudiesHumansIncidenceMiddle AgedObesityProspective StudiesRisk FactorsSpainVitaminsVitamin DVitaminscancercohortobesityvitamin D

Identifiers

PMID35807746
PMCPMC9268452
OpenAlexW4283261240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.