Evidence map›Paper›PMID 35807618›Full record

ArticlePlants (Basel, Switzerland)2022

Bulgarian Medicinal Extracts as Natural Inhibitors with Antiviral and Antibacterial Activity.

Ivanka Nikolova, Tsvetelina Paunova-Krasteva, Zdravka Petrova, Petar Grozdanov, Nadya Nikolova, Georgi Tsonev, Alexandros Triantafyllidis, Stoyan Andreev, Madlena Trepechova, Viktoria Milkova and 1 more

Open access · goldAbstract read
In one paragraph

Article in Plants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Interference ofPharmaceuticals (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Ivanka NikolovaDepartment of Virology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Georgi Bonchev, 1113 Sofia, Bulgaria.ORCID 0000-0001-9130-6600
Tsvetelina Paunova-KrastevaDepartment of General Microbiology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Georgi Bonchev, 1113 Sofia, Bulgaria.
Zdravka PetrovaDepartment of Virology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Georgi Bonchev, 1113 Sofia, Bulgaria.
Petar GrozdanovLaboratory Center Pasteur, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Georgi Bonchev, 1113 Sofia, Bulgaria.ORCID 0000-0003-2788-382X
Nadya NikolovaDepartment of Virology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Georgi Bonchev, 1113 Sofia, Bulgaria.
Georgi TsonevDepartment of Virology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Georgi Bonchev, 1113 Sofia, Bulgaria.
Alexandros TriantafyllidisDepartment of Virology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Georgi Bonchev, 1113 Sofia, Bulgaria.
Stoyan AndreevDepartment of Virology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Georgi Bonchev, 1113 Sofia, Bulgaria.ORCID 0000-0001-6856-9541
Madlena TrepechovaDepartment of Virology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Georgi Bonchev, 1113 Sofia, Bulgaria.
Viktoria MilkovaInstitute of Physical Chemistry, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Neli Vilhelmova-IlievaDepartment of Virology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Georgi Bonchev, 1113 Sofia, Bulgaria.ORCID 0000-0003-4772-4471
Bulgarian Academy of Sciences · BG

Funding

National Science Fund at the Ministry of Education and Science, Bulgaria КП-06-ДК1/3
6 · The paper itself

Abstract

backgroundBulgaria is a country with a wide range of medicinal plants, with uses in traditional medicine dating back for centuries.

methodsDisc diffusion assay was used to evaluate the antimicrobial activity of the plant extracts. A cytopathic effect inhibition test was used for the assessment of the antiviral activity of the extracts. The virucidal activity of the extracts, their influence on the stage of viral adsorption, and their protective effect on uninfected cells were reported using the end-point dilution method, and Δlgs was determined as compared to the untreated controls.

resultsThe results of the study reveal that the antibacterial potential of

conclusionThe antipathogenic potential of extracts of

Indexed as

antimicrobial activityherpes simplex virus-1human adenovirus-5human coronavirusnatural extractspoliovirus-1viral adsorptionvirucidal activity

Identifiers

PMID35807618
PMCPMC9268788
OpenAlexW4283386495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.