Evidence map›Paper›PMID 35807531›Full record

ArticleMolecules (Basel, Switzerland)2022

Effective Isolation of Picrocrocin and Crocins from Saffron: From HPTLC to Working Standard Obtaining.

Laurynas Jarukas, Konradas Vitkevicius, Olha Mykhailenko, Ivan Bezruk, Victoriya Georgiyants, Liudas Ivanauskas

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laurynas JarukasDepartment of Analytical and Toxicological Chemistry, Lithuanian University of Health Sciences, A. Mickeviciaus Str. 9, LT-44307 Kaunas, Lithuania.ORCID 0000-0002-0119-1406
Konradas VitkeviciusDepartment of Analytical and Toxicological Chemistry, Lithuanian University of Health Sciences, A. Mickeviciaus Str. 9, LT-44307 Kaunas, Lithuania.
Olha MykhailenkoDepartment of Pharmaceutical Chemistry, National University of Pharmacy, Valentynivska, Str. 4, 461168 Kharkiv, Ukraine.ORCID 0000-0003-3822-8409
Ivan BezrukDepartment of Pharmaceutical Chemistry, National University of Pharmacy, Valentynivska, Str. 4, 461168 Kharkiv, Ukraine.ORCID 0000-0002-1212-1649
Victoriya GeorgiyantsDepartment of Pharmaceutical Chemistry, National University of Pharmacy, Valentynivska, Str. 4, 461168 Kharkiv, Ukraine.ORCID 0000-0001-8794-8010
Liudas IvanauskasDepartment of Analytical and Toxicological Chemistry, Lithuanian University of Health Sciences, A. Mickeviciaus Str. 9, LT-44307 Kaunas, Lithuania.ORCID 0000-0001-5390-2161

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Saffron is widely cultivated and used as a spice. Recently published data on the chemical composition and pharmacological potential of saffron determine its use in pharmacy and medicine. The proposed high-performance thin-layer chromatography (HPTLC) method allows good separation of 11 analytes. The saffron quality (Iran, Ukraine, Spain, Morocco samples) assessment was based on the European Pharmacopoeia monograph and ISO 3632. The HPTLC method for the safranal, crocin, and picrocrocin quantification was proposed and validated. The crocins content in Ukrainian saffron was from 17.80% to 33.25%. Based on qualitative and quantitative assessment results, the saffron sample from Zaporizhzhia (Ukraine) had the highest compounds content and was chosen to obtain the working standards of picrocrocin and crocins (

Indexed as

CrocusCarotenoidsChromatography, High Pressure LiquidChromatography, Thin LayerCyclohexenesGlucosidesPlant ExtractsTandem Mass SpectrometryTerpenesCarotenoidscrocinCyclohexenesGlucosidespicrocrocinPlant ExtractsTerpenescrocinsHPTLCpicrocrocinpreparative chromatographyquality controlsaffronUPLC-ESI-MS/MS

Identifiers

PMID35807531
PMCPMC9267943

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.