Evidence map›Paper›PMID 35807290›Full record

ArticleMolecules (Basel, Switzerland)2022

Pharmacological Inhibition of Endogenous Hydrogen Sulfide Attenuates Breast Cancer Progression.

Nazeer Hussain Khan, Di Wang, Wenkang Wang, Muhammad Shahid, Saadullah Khattak, Ebenezeri Erasto Ngowi, Muhammad Sarfraz, Xin-Ying Ji, Chun-Yang Zhang, Dong-Dong Wu

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Sulfide regulation and catabolism in health and disease.Signal transduction and targeted therapy · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Emerging roles of hydrogen sulfide-metabolizing enzymes in cancer.Redox report : communications in free radical research · 2024
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Dual targeting of HHeliyon · 2023
    Article
  16. The Triple Crown: NO, CO, and HPharmacology & therapeutics · 2023
    Review
  17. Article
  18. Natural Products for Chronic Diseases: A Ray of Hope.Molecules (Basel, Switzerland) · 2022
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

Nazeer Hussain KhanHenan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.ORCID 0000-0003-4380-233X
Di WangHenan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.
Wenkang WangDepartment of Breast Surgery, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, China.ORCID 0000-0002-6325-1267
Muhammad ShahidDepartment of Biological Sciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi 43600, Malaysia.ORCID 0000-0001-5487-641X
Saadullah KhattakHenan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.ORCID 0000-0001-6798-2991
Ebenezeri Erasto NgowiHenan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.ORCID 0000-0003-4448-5276
Muhammad SarfrazHenan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.ORCID 0000-0003-1363-7935
Xin-Ying JiHenan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.
Chun-Yang ZhangDepartment of Thoracic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Dong-Dong WuHenan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.
Henan University · CNFirst Affiliated Hospital of Zhengzhou University · CNNational University of Malaysia · MYUniversity of Lahore · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogen sulfide (H

Indexed as

Breast NeoplasmsHydrogen SulfideAnimalsCystathionineCystathionine beta-SynthaseCystathionine gamma-LyaseFemaleHumansMiceMice, NudeMolecular Docking SimulationPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReproducibility of ResultsTOR Serine-Threonine KinasesCystathionineCystathionine beta-SynthaseCystathionine gamma-LyaseHydrogen SulfidePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktTOR Serine-Threonine Kinasesapoptosisbreast cancerendogenous hydrogen sulfidesignaling pathwaytumor growth

Identifiers

PMID35807290
PMCPMC9268373
OpenAlexW4283376823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.