Evidence map›Paper›PMID 35807274›Full record

ArticleMolecules (Basel, Switzerland)2022

Identifying Major Drivers of Antioxidant Activities in Complex Polyphenol Mixtures from Grape Canes.

Manon Ferrier, Kévin Billet, Samantha Drouet, Duangjai Tungmunnithum, Magdalena Anna Malinowska, Cécile Marchal, Sandrine Dedet, Nathalie Giglioli-Guivarc'h, Christophe Hano, Arnaud Lanoue

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. A Metabolome Atlas of Grape Biodiversity.Journal of agricultural and food chemistry · 2026
    Article
  2. Article
  3. Relationship Between the Structure of the FlavoneMolecules (Basel, Switzerland) · 2024
    Article
  4. Review
  5. Shoot Cultures ofMolecules (Basel, Switzerland) · 2023
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Manon FerrierEA 2106 Biomolécules et Biotechnologies Végétales, UFR des Sciences Pharmaceutiques, Université de Tours, 31 Av. Monge, 37200 Tours, France.ORCID 0000-0002-6719-8125
Kévin BilletEA 2106 Biomolécules et Biotechnologies Végétales, UFR des Sciences Pharmaceutiques, Université de Tours, 31 Av. Monge, 37200 Tours, France.
Samantha DrouetLaboratoire de Biologie des Ligneux et des Grandes Cultures (LBLGC), INRA USC1328 Université d'Orléans, CEDEX 2, 45067 Orléans, France.
Duangjai TungmunnithumLaboratoire de Biologie des Ligneux et des Grandes Cultures (LBLGC), INRA USC1328 Université d'Orléans, CEDEX 2, 45067 Orléans, France.ORCID 0000-0002-4552-6191
Magdalena Anna MalinowskaEA 2106 Biomolécules et Biotechnologies Végétales, UFR des Sciences Pharmaceutiques, Université de Tours, 31 Av. Monge, 37200 Tours, France.ORCID 0000-0001-9172-7341
Cécile MarchalGrapevine Biological Resources Center, INRAE, Unité Expérimentale Domaine de Vassal, University of Montpellier, 34340 Marseillan, France.
Sandrine DedetGrapevine Biological Resources Center, INRAE, Unité Expérimentale Domaine de Vassal, University of Montpellier, 34340 Marseillan, France.
Nathalie Giglioli-Guivarc'hEA 2106 Biomolécules et Biotechnologies Végétales, UFR des Sciences Pharmaceutiques, Université de Tours, 31 Av. Monge, 37200 Tours, France.ORCID 0000-0003-4261-5137
Christophe HanoLaboratoire de Biologie des Ligneux et des Grandes Cultures (LBLGC), INRA USC1328 Université d'Orléans, CEDEX 2, 45067 Orléans, France.ORCID 0000-0001-9938-0151
Arnaud LanoueEA 2106 Biomolécules et Biotechnologies Végétales, UFR des Sciences Pharmaceutiques, Université de Tours, 31 Av. Monge, 37200 Tours, France.ORCID 0000-0002-7377-8177
Université de Tours · FRUniversité d'Orléans · FRUniversité de Montpellier · FR

Funding

Région Centre Val de Loire CEPATLAS, VINOCOSM and INNOCOSM
6 · The paper itself

Abstract

Grape canes represent a valuable source of numerous polyphenols with antioxidant properties, whose compositions vary depending on the genotype and environmental factors. Antioxidant activities of pure molecules are often reported without considering possible interactions that may occur in complex polyphenol mixture. Using UPLC-MS-based metabolomics and unsupervised classification, we explored the polyphenol variations in grape cane extracts from a collection of European varieties. Antioxidant activities were assessed using ORAC, ABTS, DPPH, FRAP, CUPRAC and chelation assays. Pairwise correlations between polyphenols and antioxidant capacities were performed to identify molecules that contributed more to the antioxidant capacities within a complex mixture of polyphenols.

Indexed as

PolyphenolsVitisAntioxidantsChromatography, LiquidPlant ExtractsTandem Mass SpectrometryAntioxidantsPlant ExtractsPolyphenolsantioxidant activitiesgrape canesgrape varietiesmetabolomicspolyphenols

Identifiers

PMID35807274
PMCPMC9268674
OpenAlexW4283391919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.