Evidence map›Paper›PMID 35807244›Full record

ArticleMolecules (Basel, Switzerland)2022

Potent Activity of a High Concentration of Chemical Ozone against Antibiotic-Resistant Bacteria.

Karyne Rangel, Fellipe O Cabral, Guilherme C Lechuga, João P R S Carvalho, Maria H S Villas-Bôas, Victor Midlej, Salvatore G De-Simone

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Advances in Ozone-Based Inactivation of SARS-CoV-2: An Updated Review.International journal of molecular sciences · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Effectiveness Evaluation of a UV-C-Photoinactivator against Selected ESKAPE-E Pathogens.International journal of environmental research and public health · 2022
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Karyne RangelCenter for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), FIOCRUZ, Rio de Janeiro 21040-900, Brazil.
Fellipe O CabralMicrobiology Department, National Institute for Quality Control in Health (INCQS), FIOCRUZ, Rio de Janeiro 21040-900, Brazil.
Guilherme C LechugaCenter for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), FIOCRUZ, Rio de Janeiro 21040-900, Brazil.
João P R S CarvalhoCenter for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), FIOCRUZ, Rio de Janeiro 21040-900, Brazil.
Maria H S Villas-BôasMicrobiology Department, National Institute for Quality Control in Health (INCQS), FIOCRUZ, Rio de Janeiro 21040-900, Brazil.
Victor MidlejLaboratory of Cellular and Ultrastructure, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-900, Brazil.ORCID 0000-0001-9294-6597
Salvatore G De-SimoneCenter for Technological Development in Health (CDTS), National Institute of Science and Technology for Innovation in Neglected Population Diseases (INCT-IDPN), FIOCRUZ, Rio de Janeiro 21040-900, Brazil.
Fundação Oswaldo Cruz · BRNational Council for Scientific and Technological Development · BRUniversidade Federal Fluminense · BR

Funding

Brazilian Council for Scientific Research (CNPq) #467.488.2014-2; #3075732011; #3013322015-0Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro (FAPERJ ) $110.198-13; #202.841-2018
6 · The paper itself

Abstract

backgroundHealth care-associated infections (HAIs) are a significant public health problem worldwide, favoring multidrug-resistant (MDR) microorganisms. The SARS-CoV-2 infection was negatively associated with the increase in antimicrobial resistance, and the ESKAPE group had the most significant impact on HAIs. The study evaluated the bactericidal effect of a high concentration of O MATERIAL AND

methodsFour standard strains and four clinical or environmental MDR strains were exposed to elevated ozone doses at different concentrations and times. Bacterial inactivation (growth and cultivability) was investigated using colony counts and resazurin as metabolic indicators. Scanning electron microscopy (SEM) was performed.

resultsThe culture exposure to a high level of O

Indexed as

COVID-19 Drug TreatmentCross InfectionOzoneAnti-Bacterial AgentsBacteriaHumansPseudomonas aeruginosaSARS-CoV-2Staphylococcus aureusAnti-Bacterial AgentsOzoneantimicrobial activityantimicrobial resistanceESKAPE pathogensozonepathogenic bacteriaSEM

Identifiers

PMID35807244
PMCPMC9268618
OpenAlexW4283270520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.