Evidence map›Paper›PMID 35807235›Full record

ArticleMolecules (Basel, Switzerland)2022

Binding Studies of Caffeic and p-Coumaric Acid with α-Amylase: Multispectroscopic and Computational Approaches Deciphering the Effect on Advanced Glycation End Products (AGEs).

Mohd Shahnawaz Khan, Majed S Alokail, Amal Majed H Alenad, Nojood Altwaijry, Nouf Omar Alafaleq, Abdulaziz Mohammed Alamri, Mubarak Ali Zawba

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Anti-Glucotoxicity Effect of PhytoconstituentsInternational journal of molecular sciences · 2023
    Review
  10. Valorization of Rice Husk (Foods (Basel, Switzerland) · 2023
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mohd Shahnawaz KhanDepartment of Biochemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Majed S AlokailDepartment of Biochemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Amal Majed H AlenadDepartment of Biochemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Nojood AltwaijryDepartment of Biochemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0001-7367-8312
Nouf Omar AlafaleqDepartment of Biochemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0003-1868-4706
Abdulaziz Mohammed AlamriDepartment of Biochemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Mubarak Ali ZawbaDepartment of Biochemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
King Saud University · SA

Funding

Research support programme, KSU RSP 2021/352
6 · The paper itself

Abstract

Alpha-amylase (α-amylase) is a key player in the management of diabetes and its related complications. This study was intended to have an insight into the binding of caffeic acid and coumaric acid with α-amylase and analyze the effect of these compounds on the formation of advanced glycation end-products (AGEs). Fluorescence quenching studies suggested that both the compounds showed an appreciable binding affinity towards α-amylase. The evaluation of thermodynamic parameters (Δ

Indexed as

alpha-AmylasesCoumaric AcidsGlycation End Products, AdvancedMolecular Docking SimulationSulfhydryl Compoundsalpha-AmylasesCoumaric AcidsGlycation End Products, Advancedp-coumaric acidSulfhydryl Compoundsadvanced glycation end-productscaffeic acidcoumaric acidα-amylase

Identifiers

PMID35807235
PMCPMC9267998
OpenAlexW4283361384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.