Evidence map›Paper›PMID 35807212›Full record

ArticleMolecules (Basel, Switzerland)2022

Modeling of Anticancer Sulfonamide Derivatives Lipophilicity by Chemometric and Quantitative Structure-Retention Relationships Approaches.

Monika Pastewska, Beata Żołnowska, Strahinja Kovačević, Hanna Kapica, Maciej Gromelski, Filip Stoliński, Jarosław Sławiński, Wiesław Sawicki, Krzesimir Ciura

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Anticancer Activity of Ether Derivatives of Chrysin.Molecules (Basel, Switzerland) · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Monika PastewskaDepartment of Physical Chemistry, Medical University of Gdańsk, Al. Gen. Hallera 107, 80-416 Gdańsk, Poland.
Beata ŻołnowskaDepartment of Organic Chemistry, Medical University of Gdańsk, Al. Gen. Hallera 107, 80-416 Gdańsk, Poland.ORCID 0000-0003-2007-5168
Strahinja KovačevićDepartment of Applied and Engineering Chemistry, Faculty of Technology Novi Sad, University of Novi Sad, Bulevar Cara Lazara 1, 21000 Novi Sad, Serbia.ORCID 0000-0002-5619-9894
Hanna KapicaDepartment of Physical Chemistry, Medical University of Gdańsk, Al. Gen. Hallera 107, 80-416 Gdańsk, Poland.
Maciej GromelskiQSAR Lab Ltd., Trzy Lipy 3 St., 80-172 Gdańsk, Poland.
Filip StolińskiQSAR Lab Ltd., Trzy Lipy 3 St., 80-172 Gdańsk, Poland.
Jarosław SławińskiDepartment of Organic Chemistry, Medical University of Gdańsk, Al. Gen. Hallera 107, 80-416 Gdańsk, Poland.ORCID 0000-0003-2794-5031
Wiesław SawickiDepartment of Physical Chemistry, Medical University of Gdańsk, Al. Gen. Hallera 107, 80-416 Gdańsk, Poland.
Krzesimir CiuraDepartment of Physical Chemistry, Medical University of Gdańsk, Al. Gen. Hallera 107, 80-416 Gdańsk, Poland.

Funding

Ministry of Science and Higher Education ST3 02-0003/07/518
6 · The paper itself

Abstract

Sulfonamides are a classic group of chemotherapeutic drugs with a broad spectrum of pharmacological action, including anticancer activity. In this work, reversed-phase high-performance liquid chromatography and biomimetic chromatography were applied to characterize the lipophilicity of sulfonamide derivatives with proven anticancer activities against human colon cancer. Chromatographically determined lipophilicity parameters were compared with obtained log

Indexed as

ChemometricsChromatography, Reverse-PhaseChromatography, High Pressure LiquidCluster AnalysisHumansPrincipal Component AnalysisQuantitative Structure-Activity RelationshipSulfonamidesSulfonamideslipophilicityquantitative structure-retention relationshipssulfonamide derivatives

Identifiers

PMID35807212
PMCPMC9268166

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.