ArticleJournal of clinical medicine2022
How Old Is Old? An Age-Stratified Analysis of Elderly Liver Donors above 65.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Reducing Thirty-Day Readmissions Among Geriatric Patients Through Multidisciplinary Care: A Tertiary Center Experience.Healthcare (Basel, Switzerland) · 2026Article
- Effect of Donor-Recipient Age Difference on Liver Transplant Outcomes.Transplantation direct · 2026Article
- Elderly Ages in Liver Transplantation: Are Older Donors Really Higher Risk?Transplantation direct · 2025Article
- Age and liver transplantation: a key factor in clinical outcomes? single center study in Argentina.Frontiers in aging · 2025Article
- Profile of Liver Transplant Recipient in a Tertiary Hospital in Northern Spain.Journal of clinical medicine · 2023Article
- Donor Proteinuria and Allograft Function in Kidney Transplantation: Short- and Long-Term Results From a Retrospective Cohort Study.Transplant international : official journal of the European Society for Organ Transplantation · 2023Article
- Innate Immune Cells during Machine Perfusion of Liver Grafts-The Janus Face of Hepatic Macrophages.Journal of clinical medicine · 2022Review
- Bariatric surgery in liver cirrhosis.Frontiers in surgery · 2022Article
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In liver transplantation, older donor age is a well-known risk factor for dismal outcomes, especially due to the high susceptibility of older grafts to ischemia-reperfusion injury. However, whether the factors correlating with impaired graft and patient survival following the transplantation of older grafts follow a linear trend among elderly donors remains elusive. In this study, liver transplantations between January 2006 and May 2018 were analyzed retrospectively. Ninety-two recipients of grafts from donors ≥65 years were identified and divided into two groups: (1) ≥65-69 and (2) ≥ 70 years. One-year patient survival was comparable between recipients of grafts from donors ≥65-69 and ≥70 years (78.9% and 70.0%). One-year graft survival was 73.1% (donor ≥65-69) and 62.5% (donor ≥ 70), while multivariate analysis revealed superior one-year graft survival to be associated with a donor age of ≥65-69. No statistically significant differences were found for rates of primary non-function. The influence of donor age on graft and patient survival appears not to have a distinct impact on dismal outcomes in the range of 65-70 years. The impact of old donor age needs to be balanced with other risk factors, as these donors provide grafts that offer a lifesaving graft function.
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Registered trials
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