Evidence map›Paper›PMID 35807123›Full record

ReviewJournal of clinical medicine2022

Current Effective Therapeutics in Management of COVID-19.

Kavya Atluri, Iris Aimlin, Shitij Arora

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  20. Viral proteases as therapeutic targets.Molecular aspects of medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kavya AtluriDepartment of Bioinformatics, University of California, Los Angeles, CA 90095, USA.
Iris AimlinDepartment of Internal Medicine, Montefiore Medical Center, New York, NY 10467, USA.
Shitij AroraDepartment of Internal Medicine, Division of Hospital Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY 10461, USA.ORCID 0000-0002-8927-6171

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current pandemic due to the SARS-CoV-2 virus has caused irreparable damage globally. High importance is placed on defining current therapeutics for Coronavirus Disease 2019 (COVID-19). In this review, we discuss the evidence from pivotal trials that led to the approval of effective therapeutics in the treatment and prevention of COVID-19. We categorize them as effective outpatient and inpatient management strategies The review also attempts to contextualize the efficacy of therapeutics to the emerging variants. Vaccines, which remain the most effective prevention against hospitalization and deaths is not included in this review.

Indexed as

AnakinraanticoagulationbaricitinibbebtelovimabCasirivimab plus imdevimabcoronavirus disease 2019corticosteroidsCOVID-19evusheldmolnupiravirmonoclonal antibodiesomicronpaxlovidremdesivirSotrovimabtherapeuticstimelinetocilizumab

Identifiers

PMID35807123
PMCPMC9267414

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.