Evidence map›Paper›PMID 35807111›Full record

ArticleJournal of clinical medicine2022

High Yield of Chest X-ray in the Follow-Up of Colorectal Cancer.

Eline G M Steenhuis, Ivonne J H Schoenaker, Jan Willem B De Groot, Jos A Stigt, Onne Reerink, Wouter H De Vos Tot Nederveen Cappel, Henderik L Van Westreenen, Richard M Brohet

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Eline G M SteenhuisDepartment of Gastroenterology and Hepatology, Isala Zwolle, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Ivonne J H SchoenakerIsala Oncology Center, Isala, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Jan Willem B De GrootIsala Oncology Center, Isala, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Jos A StigtDepartment of Pulmonology, Isala, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Onne ReerinkDepartment of Radiation Oncology, Isala, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Wouter H De Vos Tot Nederveen CappelDepartment of Gastroenterology and Hepatology, Isala Zwolle, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Henderik L Van WestreenenDepartment of Surgery, Isala, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.ORCID 0000-0002-1910-2723
Richard M BrohetDepartment of Epidemiology & Statistics, Isala, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Isala · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWorldwide, colorectal carcinoma (CRC) has a high incidence and a substantial cancer-related mortality. The recurrence risk is 30-50% and lung metastases are common. Treatment of lung metastases with stereotactic ablative radiotherapy (SABR) or metastasectomy may increase survival. The best modality for thoracic screening in the follow-up, however, remains controversial. In this study, we aimed to unravel the additional value of routine chest X-ray (CXR) for detecting lung metastases during the follow-up of CRC patients treated with curative surgery.

methodsBetween 2013 and 2017, 668 CRC patients were treated with curative intent, of whom 633 patients were included in follow-up, which consisted of CXR, serum Carcino-Embryonic Antigen (CEA) and ultrasound of the liver. Patients who developed lung metastases, diagnosed with CXR and characterised by a normal concomitant serum CEA level, were identified. Number, size and treatment of lung metastases were described.

resultsThirty-four (5.4%) patients developed lung metastases. Seventeen (50%) were detected by CXR without pathological CEA levels. Eleven (65%) of these patients were treated with curative intent, whereas 21% of patients with lung metastases and elevated CEA levels were treated with curative intent (

conclusionsMore than 50% of patients with lung metastases on CXR in the follow-up would not have been detected with CEA-triggered imaging only. In addition, patients with colorectal lung metastases without elevated CEA levels were often suitable for curative treatment and, therefore, CXR seems to have additional value within the follow-up of CRC.

Indexed as

chest radiographchest X-raycolorectal cancercolorectal carcinomafollow-up

Identifiers

PMID35807111
PMCPMC9267521
OpenAlexW4283802824

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.