Evidence map›Paper›PMID 35806975›Full record

ArticleJournal of clinical medicine2022

Exploring the Differences in the Gut Microbiome in Atopic Dermatitis According to the Presence of Gastrointestinal Symptoms.

Chang-Yi Han, Soon-Kyeong Kwon, Mijung Yeom, Dae-Hyun Hahm, Jae-Woo Park, Hi-Joon Park, Kyuseok Kim

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Skin and gut microbiome in atopic dermatitis: Mechanisms and therapeutic opportunities.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Review
  3. Article
  4. Review
  5. Review
  6. Atopic Dermatitis: Beyond the Skin and Into the Gut.Journal of clinical medicine · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Chang-Yi HanDepartment of Ophthalmology, Otorhinolaryngology, and Dermatology of Korean Medicine, Graduate School of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Soon-Kyeong KwonDivision of Applied Life Science (BK21), Gyeongsang National University, Jinju 52828, Korea.
Mijung YeomAcupuncture & Meridian Science Research Center, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Dae-Hyun HahmAcupuncture & Meridian Science Research Center, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0002-5545-3125
Jae-Woo ParkDepartment of Gastroenterology, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Hi-Joon ParkAcupuncture & Meridian Science Research Center, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Kyuseok KimDepartment of Ophthalmology, Otorhinolaryngology, and Dermatology of Korean Medicine, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Kyung Hee University · KRGyeongsang National University · KR

Funding

National Research Foundation of Korea NRF-2015M3A9E3052338National Research Foundation of Korea NRF-2020R1A4A1018598
6 · The paper itself

Abstract

(1) Background: Atopic dermatitis (AD) is a multifactorial chronic allergic skin disease. Gastrointestinal (GI) functions have been suggested to be associated with its incidence or severity. As modulators of the gut-skin axis, gut microbes might affect the pathophysiology of AD. (2) Methods: We divided a cohort of patients with AD according to their GI symptoms as follows: AD with epigastric fullness (ADwEF), AD with epigastric rigidity (ADwER), and AD without GI symptoms (ADw/oGI). The gut microbial profiles were analyzed using 16S rRNA amplicon sequencing. (3) Results: The microbiota of the ADwER group showed low diversity indices in richness and evenness and formed a separate cluster to the other groups. In the ADwER group, the proportion of

Indexed as

atopic dermatitisgastrointestinal symptomsgut microbiomegut–skin axis

Identifiers

PMID35806975
PMCPMC9267706
OpenAlexW4283651920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.