Evidence map›Paper›PMID 35806931›Full record

ArticleJournal of clinical medicine2022

Sex Disparities in Outcome of Patients with Alcohol-Related Liver Cirrhosis within the Eurotransplant Network-A Competing Risk Analysis.

Stephan Listabarth, Daniel König, Gabriela Berlakovich, Petra Munda, Peter Ferenci, Dagmar Kollmann, Georg Gyöeri, Thomas Waldhoer, Magdalena Groemer, Arjan van Enckevort and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Stephan ListabarthClinical Division of Social Psychiatry, Department of Psychiatry and Psychotherapy, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-0466-0420
Daniel KönigClinical Division of Social Psychiatry, Department of Psychiatry and Psychotherapy, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-5741-834X
Gabriela BerlakovichDivision of Transplantation, Department of Surgery, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0001-8850-7874
Petra MundaDivision of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, 1090 Vienna, Austria.
Peter FerenciDivision of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-2306-1992
Dagmar KollmannDivision of Transplantation, Department of Surgery, Medical University of Vienna, 1090 Vienna, Austria.
Georg GyöeriDivision of Transplantation, Department of Surgery, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-0863-2876
Thomas WaldhoerCenter for Public Health, Department of Epidemiology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-2043-8299
Magdalena GroemerClinical Division of Social Psychiatry, Department of Psychiatry and Psychotherapy, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-3703-0399
Arjan van EnckevortEurotransplant International Foundation, 2301 Leiden, The Netherlands.
Benjamin VyssokiClinical Division of Social Psychiatry, Department of Psychiatry and Psychotherapy, Medical University of Vienna, 1090 Vienna, Austria.
Medical University of Vienna · ATEurotransplant · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol use disorder (AUD) is one of the most important risk factors for the development of alcohol-related liver cirrhosis (ALC). Importantly, psychiatrists are an integral part of the interdisciplinary care for patients with AUD and ALC. The aim of the current study was to investigate whether sex influences the outcome within this group of patients. For this purpose, data of all registrations for liver transplantations due to ALC within the Eurotransplant region from 2010 to 2019 were analyzed for sex disparities using competing risk models and in-between group comparisons. Relevant sex differences in registration numbers (24.8% female) and investigated outcomes were revealed. Risk ratios for a positive outcome, i.e., transplantation (0.74), and those of adverse outcomes, i.e., removal from waiting list (1.44) and death on waiting list (1.10), indicated a relative disadvantage for female patients with ALC. Further, women listed for liver transplantations were significantly younger than their male counterparts. Notably, sex disparities found in registration and outcome parameters were independent of differences found in the prevalence of AUD and liver transplantations. Further research is necessary to identify the underlying mechanisms and establish strategies to ensure equity and utility in liver transplantations due to ALC.

Indexed as

addictionalcohol-related liver cirrhosisalcohol use disordergender medicineliver transplantationoutcome research

Identifiers

PMID35806931
PMCPMC9267400
OpenAlexW4283372606

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.