Evidence map›Paper›PMID 35806919›Full record

ReviewJournal of clinical medicine2022

Sepsis Management in Southeast Asia: A Review and Clinical Experience.

Yatin Mehta, Rajib Paul, Raihan Rabbani, Subhash Prasad Acharya, Ushira Kapilani Withanaarachchi

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07418541 (Early Co-Administration of 30 mL/kg Crystalloid Fluid and Norepinephrine for Preventing Acute Kidney Injury in Septic Shock), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07418541 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Early Co-Administration of 30 mL/kg Crystalloid Fluid and Norepinephrine for Preventing Acute Kidney Injury in Septic Shock: A Pretest-Posttest Clinical Study

TypeinterventionalSponsorUniversitas Sumatera UtaraRan2026 to 2026Enrolled100ConditionsSeptic Shock, Acute Kidney InjuryArmsNorepinephrine, Crystalloid Fluid Resuscitation
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 4 countries.

Yatin MehtaInstitute of Critical Care and Anesthesiology, Medanta the Medicity, Sector-38, Gurugram 22001, India.ORCID 0000-0002-0888-4774
Rajib PaulInternal Medicine, Apollo Hospitals, Road Number 72, Jubilee Hills, Hyderabad 500033, India.
Raihan RabbaniCritical Care & Internal Medicine, Square Hospitals Ltd., 18 Bir Uttam Qazi NuruzzamanSarak West, Panthapath, Dhaka 1205, Bangladesh.
Subhash Prasad AcharyaCritical Care Medicine, Institute of Medicine, Tribhuvan University, Maharajgunj, Kathmandu 44618, Nepal.
Ushira Kapilani WithanaarachchiPaediatrics/NICU, Teaching Hospital Karapitiya, No. 124, Ananda Mawatha, Kithulampitiya, Galle 80000, Sri Lanka.ORCID 0000-0002-0145-7673
Apollo Hospitals · INMedanta The Medicity · INSquare Hospitals · BDTeaching Hospital Kandy · LKTribhuvan University Teaching Hospital · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis is a life-threatening condition that causes a global health burden associated with high mortality and morbidity. Often life-threatening, sepsis can be caused by bacteria, viruses, parasites or fungi. Sepsis management primarily focuses on source control and early broad-spectrum antibiotics, plus organ function support. Comprehensive changes in the way we manage sepsis patients include early identification, infective focus identification and immediate treatment with antimicrobial therapy, appropriate supportive care and hemodynamic optimization. Despite all efforts of clinical and experimental research over thirty years, the capacity to positively influence the outcome of the disease remains limited. This can be due to limited studies available on sepsis in developing countries, especially in Southeast Asia. This review summarizes the progress made in the diagnosis and time associated with sepsis, colistin resistance and chloramphenicol boon, antibiotic abuse, resource constraints and association of sepsis with COVID-19 in Southeast Asia. A personalized approach and innovative therapeutic alternatives such as CytoSorb

Indexed as

colistin resistance and chloramphenicol boonCOVID-19cytosorbsepsisseptic shock

Identifiers

PMID35806919
PMCPMC9267826
OpenAlexW4283366994

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.