ArticleJournal of clinical medicine2022
The LRINEC Score-An Indicator for the Course and Prognosis of Necrotizing Fasciitis?
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- S1 Guideline on Infected Interdigital Intertrigo (also called Gram-Negative Toe Web Infection).Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026Guideline
- Post-operative quality of life in patients with necrotizing fasciitis: a report from a ten year institutional cohort.International orthopaedics · 2026Article
- Necrotizing Fasciitis in Northern Italy: Clinical Characteristics, Risk Factors, and Prognostic Value of the LRINEC Score-A Single-Center Retrospective Case Series.Infectious disease reports · 2026Article
- Explainable machine learning differentiates necrotizing fasciitis and osteomyelitis via routine blood biomarkers.NPJ digital medicine · 2026Article
- Non-infectious Subcutaneous Emphysema of the Upper Extremity: A Unique Mimicker of Necrotizing Fasciitis - A Case Report.Journal of orthopaedic case reports · 2026Article
- Challenging management of craniocervical necrotizing fasciitis and descending mediastinitis in a low-resource setting: a case report and literature review.International journal of surgery case reports · 2026Article
- The role of prognostic scoring systems in determining mortality and morbidity in patients with Fournier's gangrene.BMC surgery · 2026Article
- Prediction of mortality in necrotizing fasciitis: comparative evaluation of established prognostic scores and a novel scoring system in a retrospective cohort.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026Article
- Article
- [Necrotizing fasciitis, part 1 : Possibilities and limitations of imaging diagnostics].Radiologie (Heidelberg, Germany) · 2025Review
- Article
- Fatal facial necrotizing fasciitis: a case report highlighting diagnostic and therapeutic challenges.Oxford medical case reports · 2025Article
- Predictive Models for Necrotizing Soft Tissue Infections: Are the Available Scores Trustable?Journal of clinical medicine · 2025Review
- Complicated and deep bacterial skin and soft tissue infections.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025Review
- Predictors of sepsis, intensive care unit admission, and death in patients hospitalized for complicated skin and soft tissue infections: Retrospective study at a large tertiary-care center.SAGE open medicine · 2025Article
- Necrotizing Fasciitis: A Retrospective Review of the Microbiological Aspects and Factors Associated with Multi-Drug Resistance from a Saudi Tertiary Care Hospital.International journal of general medicine · 2025Article
- A Rare Case of Necrotizing Fasciitis Presenting As Tarsal Tunnel Syndrome in a Patient With Uncontrolled Diabetes.Cureus · 2024Article
- Necrotizing fasciitis: treatment concepts & clinical outcomes - an institutional experience.BMC surgery · 2024Observational
- A Comparison of the Application of Two Different Scoring Systems in a Patient With Upper Limb Necrotizing Fasciitis.Cureus · 2024Article
- Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The Laboratory Risk Indicator for Necrotizing Fasciitis score (LRINEC) is a simple tool used to support early diagnosis of Necrotizing Fasciitis (NF). The aim of this study was to investigate whether the LRINEC is suitable as a progression and prognosis parameter in patients with NF. Methods: In this retrospective study, laboratory data of 70 patients with NF were analyzed. The LRINEC was calculated for every patient at the time of hospital admission and postoperatively after surgical interventions. Furthermore, the LRINEC was examined as a prognostic factor for survival. Results: The overall lethality of our series was 20 out of 70 (28.6%). A highly significant LRINEC decrease was found for serial debridements. The largest decrease was observed after the first debridement. There was a significant difference between the initial LRINEC of deceased and surviving patients. A cut off value of >6.5 (7 LRINEC points) resulted in an optimal constellation of sensitivity (70%) and specificity (60%) to predict lethality in patients with NF. Conclusions: The LRINEC significantly decreases after surgical debridement. An initial LRINEC equal or greater than seven is an independent prognostic marker for lethality and can help to identify high-risk patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.