ArticleMaterials (Basel, Switzerland)2022
Zwitterionic Polypeptoids: A Promising Class of Antifouling Bioinspired Materials.
Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Next-generation polydopamine nanocoatings advancing the understanding of surface properties and antimicrobial efficacy.Scientific reports · 2026Article
- Oxidation-induced nucleophilic substitution at the electron-rich B(12) vertex in [CBChemical science · 2025Article
- Preparation and Study of Antifouling and Fouling-Release Surface Materials from Copolymers with Anchoring Functional Groups.Materials (Basel, Switzerland) · 2023Article
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Authors and funding
3 authors.
Funding
Abstract
Biofouling caused by protein adsorption and microbial colonization remains a great challenge in many applications. In this work, we synthesized a new type of zwitterionic polypeptoid containing carboxybetaine (CB) moieties (PeptoidCB) through thiol-ene chemistry of poly(N-allylglycine) (PNAG). The zwitterionic antifouling hydrogel was subsequently prepared by co-mixing PeptoidCB with agarose, which exhibited excellent resistance to non-specific protein adsorption and bacterial adhesion. Further, PeptoidCB-modified block copolypeptoids with amphiphilic structure were synthesized to form nanoparticles in an aqueous solution with neglected protein adsorption. The ability of PeptoidCB to resist non-specific protein adsorption and bacterial adhesion makes it a promising candidate for biomedical and industrial applications.
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Registered trials
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