Evidence map›Paper›PMID 35806588›Full record

ArticleMaterials (Basel, Switzerland)2022

Assessment of Angiogenesis and Cell Survivability of an Inkjet Bioprinted Biological Implant in an Animal Model.

Beu P Oropeza, Carlos Serna, Michael E Furth, Luis H Solis, Cesar E Gonzalez, Valeria Altamirano, Daisy C Alvarado, Jesus A Castor, Jesus A Cedeno, Dante Chaparro Vega and 15 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Bioengineering Cell Therapy for Treatment of Peripheral Artery Disease.Arteriosclerosis, thrombosis, and vascular biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 1 institution in 1 country.

Beu P OropezaDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Carlos SernaDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Michael E FurthDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Luis H SolisDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Cesar E GonzalezDepartment of Chemistry and Biochemistry, The University of Texas at El Paso, El Paso, TX 79968, USA.
Valeria AltamiranoDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Daisy C AlvaradoDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Jesus A CastorDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Jesus A CedenoDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Dante Chaparro VegaDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Octavio CordovaDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Isaac G DeagueroDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Erwin I DelgadoDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Mario F Garcia DuarteDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Mirsa Gonzalez FavelaDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Alba J Leyva MarquezDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Emilio S LoeraDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Gisela LopezDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Fernanda LugoDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Tania G MiramontesDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Erik MunozDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Paola A RodriguezDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Leila M SubiaDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Arahim A Zuniga HerreraDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.
Thomas BolandDepartment of Metallurgy, Materials, and Biomedical Engineering, The University of Texas at El Paso, El Paso, TX 79968, USA.ORCID 0000-0003-2161-5699
The University of Texas at El Paso · US

Funding

Phase II of BUILDing SCHOLARSUL1GM118970 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI ALEY, STEPHEN B, BOLAND, THOMAS · 2015 to 2023
$17.9M
Phase II of BUILDing SCHOLARS - Student Training CoreTL4GM118971 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI ALEY, STEPHEN B, BOLAND, THOMAS · 2015 to 2023
$9.9M
Phase II of BUILDing SCHOLARS - Research Enrichment CoreRL5GM118969 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI ALEY, STEPHEN B, BOLAND, THOMAS · 2015 to 2023
$7.4M
National Sleep Foundation 1744621NIGMS NIH HHS RL5 GM118969NIGMS NIH HHS RL5GM118969NIGMS NIH HHS TL4 GM118971NIGMS NIH HHS TL4GM118971NIGMS NIH HHS UL1 GM118970NIGMS NIH HHS UL1GM118970
6 · The paper itself

Abstract

The rapidly growing field of tissue engineering hopes to soon address the shortage of transplantable tissues, allowing for precise control and fabrication that could be made for each specific patient. The protocols currently in place to print large-scale tissues have yet to address the main challenge of nutritional deficiencies in the central areas of the engineered tissue, causing necrosis deep within and rendering it ineffective. Bioprinted microvasculature has been proposed to encourage angiogenesis and facilitate the mobility of oxygen and nutrients throughout the engineered tissue. An implant made via an inkjet printing process containing human microvascular endothelial cells was placed in both B17-SCID and NSG-SGM3 animal models to determine the rate of angiogenesis and degree of cell survival. The implantable tissues were made using a combination of alginate and gelatin type B; all implants were printed via previously published procedures using a modified HP inkjet printer. Histopathological results show a dramatic increase in the average microvasculature formation for mice that received the printed constructs within the implant area when compared to the manual and control implants, indicating inkjet bioprinting technology can be effectively used for vascularization of engineered tissues.

Indexed as

angiogenesisbio-printinginkjet printingmicrovasculaturetissue engineering

Identifiers

PMID35806588
PMCPMC9267737
OpenAlexW4283593022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.