ArticleMaterials (Basel, Switzerland)2022
Remineralization Efficacy of Four Remineralizing Agents on Artificial Enamel Lesions: SEM-EDS Investigation.
Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Biomimetic Strategies for Subsurface Enamel Remineralization: Depth-Dependent Effects of Biomimetic Agents Compared with Fluoride.Biomimetics (Basel, Switzerland) · 2026Article
- Optimization of In Vitro White Spot Lesion Protocol: Comparative Diagnostics via Visual Inspection, Scanning Electron Microscopy, and Fluorescence Methods.Diagnostics (Basel, Switzerland) · 2026Article
- Comparative Study on the Surface Properties of Synthetic Carbonated Hydroxyapatite and Natural Hydroxyapatite Before and After Contact with Solutions with de- and Remineralization Activity.Biomimetics (Basel, Switzerland) · 2026Article
- Microhardness Recovery and Micromorphology of Demineralized Dentin Restored with Modified Glass Hybrid Material.Materials (Basel, Switzerland) · 2026Article
- Assessment of the remineralizing potential of nano-bioactive glass, nano-hydroxyapatite, and sodium fluoride on artificial carious lesions in primary teeth.BMC oral health · 2026Article
- Comparative Evaluation of Beverage-Induced Surface Alterations on Dental Enamel: An In Vitro Biomaterial Study.Bioengineering (Basel, Switzerland) · 2026Article
- Enamel Remineralization Potential of Conventional and Biomimetic Toothpaste Formulations: A Comparative In Vitro Study.Dentistry journal · 2026Article
- Integrated Characterization by EDS and Roughness as a Diagnostic Tool for Dental Enamel Degradation: An In Vitro Study.Bioengineering (Basel, Switzerland) · 2026Article
- Evaluating the remineralisation potential and clinical evidence of emerging biocompatible materials in restorative dentistry: a systematic review.Biomaterial investigations in dentistry · 2026Review
- Application of Amorphous Nanomaterials in Dentistry: A Comprehensive Review.Journal of functional biomaterials · 2025Review
- Effect of Ginger Extracts in Remineralization of White Spot Lesions: A Systematic Review and Meta-analysis.International journal of clinical pediatric dentistry · 2025Article
- Time-Effect Comparative Evaluation of Three Remineralizing Agents on Artificial Enamel Lesions: A SEM-EDX In Vitro Study.Journal of clinical medicine · 2025Article
- Integrated spectroscopic and morphological analyses reveal cellular shifts in gene-silenced melanoma CSCs.Scientific reports · 2025Article
- Advances of Hydroxyapatite Nanoparticles in Dental Implant Applications.International dental journal · 2025Review
- Comparison of the remineralization effectiveness of three remineralizing agents on artificial enamel lesions: an in vitro study.BDJ open · 2025Article
- Article
- Biomimetic Effect of Saliva on Human Tooth Enamel: A Scanning Electron Microscopic Study.International journal of dentistry · 2025Article
- Effect of Bioactive Glass into Mineral Trioxide Aggregate on the Biocompatibility and Mineralization Potential of Dental Pulp Stem Cells.Biomaterials research · 2025Article
- Hydrated Calcium Silicate in Resin Composites for Prevention of Secondary Caries.International dental journal · 2024Article
- Surface and Mineral Changes of Primary Enamel after Laser Diode Irradiation and Application of Remineralization Agents: A Comparative In Vitro Study.Children (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
10 authors.
Funding
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Abstract
Dental remineralization represents the process of depositing calcium and phosphate ions into crystal voids in demineralized enamel, producing net mineral gain and preventing early enamel lesions progression. The aim of the present study was to qualitatively and quantitatively compare the remineralizing effectiveness of four commercially available agents on enamel artificial lesions using Scanning Electron Microscopy (SEM) combined with Energy Dispersive Spectroscopy (EDS) techniques. Thirty-six extracted third molars were collected and randomly assigned to six groups (n = 6), five of which were suspended in demineralizing solution for 72 h to create enamel artificial lesions, and one serving as control: G1, treated with a mousse of casein phosphopeptide and amorphous calcium−phosphate (CPP-ACP); G2, treated with a gel containing nano-hydroxyapatite; G3, treated with a 5% SF varnish; G4, treated with a toothpaste containing ACP functionalized with fluoride and carbonate-coated with citrate; G5, not-treated artificial enamel lesions; G6, not demineralized and not treated sound enamel. G1−G4 were subjected to pH cycling over a period of seven days. Analyses of the specimens’ enamel surfaces morphology were performed by SEM and EDS. Data were statistically analyzed for multiple group comparison by one-way ANOVA/Tukey’s test (p < 0.05). The results show that the Ca/P ratio of the G5 (2.00 ± 0.07) was statistically different (p < 0.05) from G1 (1.73 ± 0.05), G2 (1.76 ± 0.01), G3 (1.88 ± 0.06) and G6 (1.74 ± 0.04), while there were no differences (p > 0.05) between G1, G2 and G6 and between G4 (2.01 ± 0.06) and G5. We concluded that G1 and G2 showed better surface remineralization than G3 and G4, after 7 days of treatment.
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