Evidence map›Paper›PMID 35806361›Full record

ReviewInternational journal of molecular sciences2022

Alternative Splicing and Its Roles in Plant Metabolism.

Pui Ying Lam, Lanxiang Wang, Clive Lo, Fu-Yuan Zhu

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Alternative splicing rewires banana aroma biosynthesis.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Comprehensive identification ofFrontiers in plant science · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Gene Expression ofACS omega · 2025
    Article
  14. Article
  15. Article
  16. Review
  17. Identification ofPlants (Basel, Switzerland) · 2024
    Article
  18. A Genome-Wide Alternative Splicing Analysis ofPlants (Basel, Switzerland) · 2024
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Pui Ying LamCenter for Crossover Education, Graduate School of Engineering Science, Akita University, Tegata Gakuen-machi 1-1, Akita City 010-8502, Akita, Japan.ORCID 0000-0001-5025-1308
Lanxiang WangCo-Innovation Center for Sustainable Forestry in Southern China, College of Biology and the Environment, Nanjing Forestry University, Nanjing 210037, China.
Clive LoSchool of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong, China.ORCID 0000-0002-1995-3843
Fu-Yuan ZhuCo-Innovation Center for Sustainable Forestry in Southern China, College of Biology and the Environment, Nanjing Forestry University, Nanjing 210037, China.ORCID 0000-0002-8276-0550
Nanjing Forestry University · CNAkita University · JPUniversity of Hong Kong · HK

Funding

Jiangsu Agricultural Science and Technology Innovation Fund CX (21) 2023Natural Science Foundation of Jiangsu Province SBK2020042924Reiwa 4 Akita University manuscript submission support project
6 · The paper itself

Abstract

Plant metabolism, including primary metabolism such as tricarboxylic acid cycle, glycolysis, shikimate and amino acid pathways as well as specialized metabolism such as biosynthesis of phenolics, alkaloids and saponins, contributes to plant survival, growth, development and interactions with the environment. To this end, these metabolic processes are tightly and finely regulated transcriptionally, post-transcriptionally, translationally and post-translationally in response to different growth and developmental stages as well as the constantly changing environment. In this review, we summarize and describe the current knowledge of the regulation of plant metabolism by alternative splicing, a post-transcriptional regulatory mechanism that generates multiple protein isoforms from a single gene by using alternative splice sites during splicing. Numerous genes in plant metabolism have been shown to be alternatively spliced under different developmental stages and stress conditions. In particular, alternative splicing serves as a regulatory mechanism to fine-tune plant metabolism by altering biochemical activities, interaction and subcellular localization of proteins encoded by splice isoforms of various genes.

Indexed as

Alternative SplicingPlantsProtein IsoformsRNA Splice SitesProtein IsoformsRNA Splice Sitesalkaloidsalternative splicingascorbatelipidsmetabolismphenylpropanoidsphytohormonesplantsstarchterpenoids

Identifiers

PMID35806361
PMCPMC9266299
OpenAlexW4283793444

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.