Evidence map›Paper›PMID 35806312›Full record

ReviewInternational journal of molecular sciences2022

Connexin and Pannexin Large-Pore Channels in Microcirculation and Neurovascular Coupling Function.

Pía C Burboa, Mariela Puebla, Pablo S Gaete, Walter N Durán, Mauricio A Lillo

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Pannexins in the vasculature.American journal of physiology. Heart and circulatory physiology · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Pía C BurboaDepartment of Pharmacology, Physiology and Neuroscience, New Jersey Medical School, Rutgers University, 185 South Orange Avenue, Newark, NJ 07103, USA.
Mariela PueblaDepartamento de Morfología y Función, Facultad de Salud y Ciencias Sociales, Sede Santiago Centro, Universidad de las Américas, Avenue República 71, Santiago 8370040, Chile.ORCID 0000-0002-7756-2023
Pablo S GaeteDepartment of Physiology and Membrane Biology, University of California at Davis, Davis, CA 95616, USA.
Walter N DuránDepartment of Pharmacology, Physiology and Neuroscience, New Jersey Medical School, Rutgers University, 185 South Orange Avenue, Newark, NJ 07103, USA.
Mauricio A LilloDepartment of Pharmacology, Physiology and Neuroscience, New Jersey Medical School, Rutgers University, 185 South Orange Avenue, Newark, NJ 07103, USA.ORCID 0000-0002-2823-6619
Rutgers, The State University of New Jersey · USUniversity of California, Davis · USUniversity of the Americas · CL

Funding

Inactivation Mechanisms of Microvascular HyperpermeabilityR01HL146539 · NHLBI · RBHS-NEW JERSEY MEDICAL SCHOOL · PI DURAN, WALTER N. · 2020 to 2022
$1.9M
American Heart Association 932684NIH HHS R01 HL 146539-01A1
6 · The paper itself

Abstract

Microcirculation homeostasis depends on several channels permeable to ions and/or small molecules that facilitate the regulation of the vasomotor tone, hyperpermeability, the blood-brain barrier, and the neurovascular coupling function. Connexin (Cxs) and Pannexin (Panxs) large-pore channel proteins are implicated in several aspects of vascular physiology. The permeation of ions (i.e., Ca

Indexed as

ConnexinsNeurovascular CouplingGap JunctionsIon ChannelsMicrocirculationConnexinsIon Channelsgap junctionhemichannelsmicrocirculation

Identifiers

PMID35806312
PMCPMC9266979
OpenAlexW4283761213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.