Evidence map›Paper›PMID 35806296›Full record

ArticleInternational journal of molecular sciences2022

Effects of Ethanol on Expression of Coding and Noncoding RNAs in Murine Neuroblastoma Neuro2a Cells.

Mi Ran Choi, Sinyoung Cho, Dai-Jin Kim, Jung-Seok Choi, Yeung-Bae Jin, Miran Kim, Hye Jin Chang, Seong Ho Jeon, Young Duk Yang, Sang-Rae Lee

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Mi Ran ChoiLaboratory Animal Research Center, Ajou University School of Medicine, Suwon 16499, Korea.
Sinyoung ChoDepartment of Pharmacy, College of Pharmacy and Institute of Pharmaceutical Sciences, CHA University, Pocheon 11160, Korea.
Dai-Jin KimDepartment of Psychiatry, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Jung-Seok ChoiDepartment of Psychiatry, Samsung Medical Center, Seoul 06351, Korea.ORCID 0000-0003-2139-0522
Yeung-Bae JinDepartment of Laboratory Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea.
Miran KimDepartment of Obstetrics and Gynecology, Ajou University School of Medicine, Suwon 16499, Korea.
Hye Jin ChangDepartment of Obstetrics and Gynecology, Ajou University School of Medicine, Suwon 16499, Korea.
Seong Ho JeonDepartment of Pharmacy, College of Pharmacy and Institute of Pharmaceutical Sciences, CHA University, Pocheon 11160, Korea.
Young Duk YangDepartment of Pharmacy, College of Pharmacy and Institute of Pharmaceutical Sciences, CHA University, Pocheon 11160, Korea.
Sang-Rae LeeLaboratory Animal Research Center, Ajou University School of Medicine, Suwon 16499, Korea.
Ajou University · KRCHA University · KRGyeongsang National University · KRSamsung Medical Center · KRThe Catholic University of Korea Seoul St. Mary's Hospital · KR

Funding

Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Wel-fare HR21C1003National Research Foundation of Korea (NRF) funded by the Ministry of Education NRF-2018R1D1A1B07043055
6 · The paper itself

Abstract

Excessive use of alcohol can induce neurobiological and neuropathological alterations in the brain, including the hippocampus and forebrain, through changes in neurotransmitter systems, hormonal systems, and neuroimmune processes. We aimed to investigate the effects of ethanol on the expression of coding and noncoding RNAs in a brain-derived cell line exposed to ethanol. After exposing Neuro2a cells, a neuroblastoma cell line, to ethanol for 24 and 72 h, we observed cell proliferation and analyzed up- and downregulated mRNAs and long noncoding RNAs (lncRNAs) using total RNA-Seq technology. We validated the differential expression of some mRNAs and lncRNAs by RT-qPCR and analyzed the expression of

Indexed as

NeuroblastomaRNA, Long NoncodingAnimalsCell ProliferationEthanolGene Expression ProfilingMiceRNA, MessengerEthanolRNA, Long NoncodingRNA, MessengerCebpdethanollncRNARnu3atranscriptome profiling

Identifiers

PMID35806296
PMCPMC9267046
OpenAlexW4283783299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.