Evidence map›Paper›PMID 35806288›Full record

ArticleInternational journal of molecular sciences2022

The p.Pro482Ala Variant in the CNNM2 Gene Causes Severe Hypomagnesemia Amenable to Treatment with Spironolactone.

Ioannis Petrakis, Eleni Drosataki, Ioanna Stavrakaki, Kleio Dermitzaki, Dimitra Lygerou, Myrto Konidaki, Christos Pleros, Nikolaos Kroustalakis, Sevasti Maragkou, Ariadni Androvitsanea and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Two novel variants inFrontiers in genetics · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Ioannis PetrakisNephrology Department, Heraklion University Hospital, 71500 Heraklion, Greece.ORCID 0000-0002-0095-9823
Eleni DrosatakiNephrology Department, Heraklion University Hospital, 71500 Heraklion, Greece.
Ioanna StavrakakiNephrology Department, Heraklion University Hospital, 71500 Heraklion, Greece.
Kleio DermitzakiNephrology Department, Heraklion University Hospital, 71500 Heraklion, Greece.
Dimitra LygerouNephrology Department, Heraklion University Hospital, 71500 Heraklion, Greece.
Myrto KonidakiNephrology Department, Heraklion University Hospital, 71500 Heraklion, Greece.
Christos PlerosNephrology Department, Heraklion University Hospital, 71500 Heraklion, Greece.
Nikolaos KroustalakisNephrology Department, Heraklion University Hospital, 71500 Heraklion, Greece.
Sevasti MaragkouNephrology Department, Heraklion University Hospital, 71500 Heraklion, Greece.
Ariadni AndrovitsaneaNephrology Department, Heraklion University Hospital, 71500 Heraklion, Greece.
Ioannis StylianouInstitute of Applied and Computational Mathematics of FORTH (Foundation of Research and Technology-Hellas), 70013 Heraklion, Greece.
Ioannis ZaganasNeurogenetics Laboratory Medical School, University of Crete, 71003 Heraklion, Greece.ORCID 0000-0002-0774-5772
Kostas StylianouNephrology Department, Heraklion University Hospital, 71500 Heraklion, Greece.ORCID 0000-0003-3678-9421
University Hospital of Heraklion · GRFoundation for Research and Technology Hellas · GRUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal hypomagnesemia syndromes involving

Indexed as

Cation Transport ProteinsSpironolactoneAmino Acid SubstitutionKidneyMagnesiumCation Transport ProteinsMagnesiumSpironolactoneCNNM2HOMG6hypomagnesemiawhole exome sequencing

Identifiers

PMID35806288
PMCPMC9266752
OpenAlexW4283761914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.