ReviewInternational journal of molecular sciences2022
Cellular Conditions Responsible for Methylmercury-Mediated Neurotoxicity.
Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 42 citations in OpenAlex.
- Mitochondria-Targeted Colorimetric and Ratiometric Fluorescent Probe for HgMolecules (Basel, Switzerland) · 2026Article
- Modulation of the PI3K/AKT/mTOR and AMPK/TSC2/mTOR Pathways by N-Acetyl-L-Cysteine as a Protector of Embryonic Bodies from the Toxic Effect of Methylmercury.Brain sciences · 2026Review
- A Large Stokes Shift Reaction-Based Colorimetric and Ratiometric Fluorescent Probe for HgJournal of fluorescence · 2026Article
- A mitochondria-targeted NIR ratiometric and colorimetric fluorescent probe with large Stokes shift for HgMikrochimica acta · 2025Article
- Mercury poisoning in women and infants inhabiting the Gangetic plains of Bihar: risk assessment.BMC public health · 2025Article
- SRXN1 is a novel protective factor against methylmercury-induced apoptosis in C17.2 mouse neural stem cells.Toxicological research · 2025Article
- A Reaction-Based ESIPT Fluorescent Probe for the Detection of HgJournal of fluorescence · 2025Article
- Heavy Metal Contamination: Sources, Health Impacts, and Sustainable Mitigation Strategies with Insights from Nigerian Case Studies.F1000Research · 2025Review
- Treadmill exercise protects against methylmercury neurotoxicity by increasing BDNF in the mouse brain.Environmental health and preventive medicine · 2025Article
- Differential Modulatory Effects of Methylmercury (MeHg) on Ahr-regulated Genes in Extrahepatic Tissues of C57BL/6 Mice.Biological trace element research · 2024Article
- Cohort profile: China undergraduate cohort for environmental health study.BMC public health · 2024Article
- Trends in Mercury Contamination Distribution among Human and Animal Populations in the Amazon Region.Toxics · 2024Review
- Conversion of methylmercury into inorganic mercury via organomercurial lyase (MerB) activates autophagy and aggresome formation.Scientific reports · 2023Article
- Recent insights into autophagy and metals/nanoparticles exposure.Toxicological research · 2023Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Methylmercury (MeHg) is a widely known environmental pollutant that causes severe neurotoxicity. MeHg-induced neurotoxicity depends on various cellular conditions, including differences in the characteristics of tissues and cells, exposure age (fetal, childhood, or adulthood), and exposure levels. Research has highlighted the importance of oxidative stress in the pathogenesis of MeHg-induced toxicity and the site- and cell-specific nature of MeHg-induced neurotoxicity. The cerebellar granule cells and deeper layer cerebrocortical neurons are vulnerable to MeHg. In contrast, the hippocampal neurons are resistant to MeHg, even at high mercury accumulation levels. This review summarizes the mechanisms underlying MeHg-mediated intracellular events that lead to site-specific neurotoxicity. Specifically, we discuss the mechanisms associated with the redox ability, neural outgrowth and synapse formation, cellular signaling pathways, epigenetics, and the inflammatory conditions of microglia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.