Evidence map›Paper›PMID 35806218›Full record

ReviewInternational journal of molecular sciences2022

The Therapeutic Potential of the Restoration of the p53 Protein Family Members in the

Matilde Fregni, Yari Ciribilli, Joanna E Zawacka-Pankau

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Zebrafish frk Gene Knockout Shows Social Impairments Relevant to Autism and Delays Brain Development by Increasing Cell Proliferation.Autism research : official journal of the International Society for Autism Research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 3 countries.

Matilde FregniDepartment of Cellular, Computational, and Integrative Biology (CIBIO), University of Trento, 38123 Povo, TN, Italy.
Yari CiribilliDepartment of Cellular, Computational, and Integrative Biology (CIBIO), University of Trento, 38123 Povo, TN, Italy.ORCID 0000-0001-9231-379X
Joanna E Zawacka-PankauCenter for Hematology and Regenerative Medicine, Department of Medicine, Huddinge, Karolinska Institutet, 141 86 Stockholm, Sweden.ORCID 0000-0002-7415-2942
University of Trento · ITMedical University of Warsaw · PL

Funding

National Science Centre Poland 2020/39/B/NZ7/00757
6 · The paper itself

Abstract

Despite the recent development of precision medicine and targeted therapies, lung cancer remains the top cause of cancer-related mortality worldwide. The patients diagnosed with metastatic disease have a five-year survival rate lower than 6%. In metastatic disease,

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsDrug Resistance, NeoplasmErbB ReceptorsHumansMutationProtein Kinase InhibitorsTumor Suppressor Protein p53EGFR protein, humanErbB ReceptorsProtein Kinase InhibitorsTumor Suppressor Protein p53drug repurposingEGFRlung cancermolecular targeted therapiesp53p73TKI resistance

Identifiers

PMID35806218
PMCPMC9267050
OpenAlexW4284993719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.