Evidence map›Paper›PMID 35806137›Full record

ArticleInternational journal of molecular sciences2022

Outcome Prediction in Critically-Ill Patients with Venous Thromboembolism and/or Cancer Using Machine Learning Algorithms: External Validation and Comparison with Scoring Systems.

Vasiliki Danilatou, Stylianos Nikolakakis, Despoina Antonakaki, Christos Tzagkarakis, Dimitrios Mavroidis, Theodoros Kostoulas, Sotirios Ioannidis

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

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  13. Semi-Supervised Learning to Improve Generalizability of Cancer Associated-Venous Thromboembolism Risk Prediction Models.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Vasiliki DanilatouSphynx Technology Solutions, 6300 Zug, Switzerland.ORCID 0000-0001-6967-9785
Stylianos NikolakakisSchool of Electrical and Computer Engineering, Technical University of Crete, 73100 Chania, Greece.
Despoina AntonakakiInstitute of Computer Science (ICS)-Foundation for Research and Technology-Hellas (FORTH), 70013 Heraklion, Greece.ORCID 0000-0001-9081-6115
Christos TzagkarakisInstitute of Computer Science (ICS)-Foundation for Research and Technology-Hellas (FORTH), 70013 Heraklion, Greece.
Dimitrios MavroidisInstitute of Computer Science (ICS)-Foundation for Research and Technology-Hellas (FORTH), 70013 Heraklion, Greece.
Theodoros KostoulasDepartment of Information and Communication Systems Engineering, School of Engineering, University of the Aegean, 83200 Samos, Greece.ORCID 0000-0003-2201-6938
Sotirios IoannidisSchool of Electrical and Computer Engineering, Technical University of Crete, 73100 Chania, Greece.
Foundation for Research and Technology Hellas · GRTechnical University of Crete · GREuropean University Cyprus · CYUniversity of the Aegean · GR

Funding

European Union 875351
6 · The paper itself

Abstract

Intensive care unit (ICU) patients with venous thromboembolism (VTE) and/or cancer suffer from high mortality rates. Mortality prediction in the ICU has been a major medical challenge for which several scoring systems exist but lack in specificity. This study focuses on two target groups, namely patients with thrombosis or cancer. The main goal is to develop and validate interpretable machine learning (ML) models to predict early and late mortality, while exploiting all available data stored in the medical record. To this end, retrospective data from two freely accessible databases, MIMIC-III and eICU, were used. Well-established ML algorithms were implemented utilizing automated and purposely built ML frameworks for addressing class imbalance. Prediction of early mortality showed excellent performance in both disease categories, in terms of the area under the receiver operating characteristic curve (

Indexed as

NeoplasmsVenous ThromboembolismAlgorithmsCritical IllnessHumansIntensive Care UnitsMachine LearningRetrospective StudiesROC CurvecancerICUinterpretable machine learningmortalityvenous thromboembolism

Identifiers

PMID35806137
PMCPMC9266386
OpenAlexW4283654808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.