Evidence map›Paper›PMID 35806123›Full record

ArticleInternational journal of molecular sciences2022

A Combination of the Natural Molecules Gallic Acid and Carvacrol Eradicates

Maxime Gobin, Richard Proust, Stéphane Lack, Laura Duciel, Céline Des Courtils, Emmanuel Pauthe, Adeline Gand, Damien Seyer

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Potential Use of Selected Natural Compounds with Anti-Biofilm Activity.International journal of molecular sciences · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Natural compounds in the fight againstFrontiers in pharmacology · 2024
    Review
  13. Review
  14. Article
  15. Enhancement of the Antibiofilm Activity of Nisin againstPathogens (Basel, Switzerland) · 2023
    Article
  16. Alkyl Gallates as Potential Antibiofilm Agents: A Review.Molecules (Basel, Switzerland) · 2023
    Review
  17. Hydroquinones Inhibit Biofilm Formation and Virulence Factor Production inInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Maxime GobinERRMECe Laboratory, 1 rue Descartes, CY Cergy Paris University, 95031 Neuville sur Oise, France.
Richard ProustLes Laboratoires BROTHIER, 41 Rue de Neuilly, 92735 Nanterre, France.
Stéphane LackLes Laboratoires BROTHIER, 41 Rue de Neuilly, 92735 Nanterre, France.
Laura DucielLes Laboratoires BROTHIER, 41 Rue de Neuilly, 92735 Nanterre, France.
Céline Des CourtilsLes Laboratoires BROTHIER, 41 Rue de Neuilly, 92735 Nanterre, France.ORCID 0000-0003-3697-3739
Emmanuel PautheERRMECe Laboratory, 1 rue Descartes, CY Cergy Paris University, 95031 Neuville sur Oise, France.ORCID 0000-0001-7547-1438
Adeline GandERRMECe Laboratory, 1 rue Descartes, CY Cergy Paris University, 95031 Neuville sur Oise, France.
Damien SeyerERRMECe Laboratory, 1 rue Descartes, CY Cergy Paris University, 95031 Neuville sur Oise, France.ORCID 0000-0001-7510-0573
Brothier (France) · FRCY Cergy Paris Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound infection, especially the development of bacterial biofilms, delays wound healing and is a major public health concern. Bacteria in biofilms are more tolerant to antimicrobial agents, and new treatments to eradicate mature biofilms are needed. Combining antimicrobial molecules with different mechanisms of action is an attractive strategy to tackle the heterogeneous nature of microbial communities in biofilms. This study focused on three molecules of natural origin: gallic acid (G), carvacrol (K) and curcumin (Q). Their abilities, individually or in combination, to eradicate biofilms were quantified on mono- and dual-species mature biofilms of

Indexed as

Methicillin-Resistant Staphylococcus aureusWound InfectionAnti-Bacterial AgentsBiofilmsCymenesGallic AcidHumansPseudomonas aeruginosaStaphylococcus aureusAnti-Bacterial AgentscarvacrolCymenesGallic Acidbiofilmcarvacrolcombination therapiescurcumingallic acidwounds

Identifiers

PMID35806123
PMCPMC9266711
OpenAlexW4283642094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.