Evidence map›Paper›PMID 35806114›Full record

ArticleInternational journal of molecular sciences2022

Synthesis, Physicochemical Characterization, and Antibacterial Performance of Silver-Lactoferrin Complexes.

Oleksandra Pryshchepa, Paweł Pomastowski, Katarzyna Rafińska, Adrian Gołębiowski, Agnieszka Rogowska, Maciej Monedeiro-Milanowski, Gulyaim Sagandykova, Bernhard Michalke, Philippe Schmitt-Kopplin, Michał Gloc and 3 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Antimicrobial synergism of silver and zinc oxide nanoparticles with antibiotics against clinical isolate of Cutibacterium acnes.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Oleksandra PryshchepaCentre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.ORCID 0000-0001-9586-7069
Paweł PomastowskiCentre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.ORCID 0000-0002-1594-0623
Katarzyna RafińskaDepartment of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.
Adrian GołębiowskiCentre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.ORCID 0000-0001-9321-286X
Agnieszka RogowskaCentre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.
Maciej Monedeiro-MilanowskiCentre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.ORCID 0000-0003-3713-4099
Gulyaim SagandykovaCentre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.
Bernhard MichalkeResearch Unit Analytical BioGeoChemistry, Helmholtz Zentrum Muenchen, 85764 Neuherberg, Germany.ORCID 0000-0001-6376-2588
Philippe Schmitt-KopplinResearch Unit Analytical BioGeoChemistry, Helmholtz Zentrum Muenchen, 85764 Neuherberg, Germany.ORCID 0000-0003-0824-2664
Michał GlocFaculty of Materials Science and Engineering, Warsaw University of Technology, 02-507 Warsaw, Poland.
Renata DobruckaFaculty of Materials Science and Engineering, Warsaw University of Technology, 02-507 Warsaw, Poland.
Krzysztof KurzydłowskiFaculty of Mechanical Engineering, Białystok University of Technology, 15-351 Białystok, Poland.
Bogusław BuszewskiCentre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland.

Funding

Foundation for Polish Science POIR.04.04.00-00-1792/18-00
6 · The paper itself

Abstract

Antibiotic-resistant bacteria pose one of the major threats to human health worldwide. The issue is fundamental in the case of chronic wound treatment. One of the latest trends to overcome the problem is the search for new antibacterial agents based on silver. Thus, the aim of this research was to synthesize the silver-lactoferrin complex as a new generation of substances for the treatment of infected wounds. Moreover, one of the tasks was to investigate the formation mechanisms of the respective complexes and the influence of different synthesis conditions on the features of final product. The batch-sorption study was performed by applying the Langmuir and Freundlich isotherm models for the process description. Characterization of the complexes was carried out by spectroscopy, spectrometry, and separation techniques, as well as with electron microscopy. Additionally, the biological properties of the complex were evaluated, i.e., the antibacterial activity against selected bacteria and the impact on L929 cell-line viability. The results indicate the formation of a heterogeneous silver-lactoferrin complex that comprises silver nanoparticles. The complex has higher antibacterial strength than both native bovine lactoferrin and Ag

Indexed as

Metal NanoparticlesSilverAnti-Bacterial AgentsBacteriaChemical PhenomenaHumansLactoferrinMicrobial Sensitivity TestsAnti-Bacterial AgentsLactoferrinSilverantibacterial propertiescytotoxicitymetalloproteinssilver–lactoferrin nanocomplexsilver nanoparticlessorption isotherm study

Identifiers

PMID35806114
PMCPMC9266553

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.