Evidence map›Paper›PMID 35806028›Full record

ArticleInternational journal of molecular sciences2022

Songyu Dong, Weili Zheng, Nicholas Pinkerton, Jacob Hansen, Svetlana B Tikunova, Jonathan P Davis, Sarah M Heissler, Elena Kudryashova, Edward H Egelman, Dmitri S Kudryashov

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Actin isoform-specific interactions revealed byProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Antagonistic effects of actin-specific toxins onbioRxiv : the preprint server for biology · 2024
    Article
  7. Structure, regulation, and mechanisms of nonmuscle myosin-2.Cellular and molecular life sciences : CMLS · 2024
    Review
  8. Article
  9. Stabilization of F-actin bybioRxiv : the preprint server for biology · 2023
    Article
  10. Article
  11. TheToxins · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Songyu DongDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-4828-093X
Weili ZhengDepartment of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA 22903, USA.
Nicholas PinkertonDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.
Jacob HansenDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.
Svetlana B TikunovaDepartment of Physiology and Cell Biology, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.
Jonathan P DavisDepartment of Physiology and Cell Biology, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.
Sarah M HeisslerDepartment of Physiology and Cell Biology, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.
Elena KudryashovaDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-1646-1229
Edward H EgelmanDepartment of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA 22903, USA.ORCID 0000-0003-4844-5212
Dmitri S KudryashovDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-1782-3305
The Ohio State University · USUniversity of Virginia · US

Funding

Cryo-EM of Helical Protein and Nucleoprotein Polymers at Near Atomic ResolutionR35GM122510 · NIGMS · UNIVERSITY OF VIRGINIA · PI EDWARD H. EGELMAN · 2017 to 2026
$7.3M
Regulation and Dysregulation of Cardiac EC coupling by CalmodulinR01HL138579 · NHLBI · OHIO STATE UNIVERSITY · PI Jonathan Paul Davis, Sandor Gyorke · 2017 to 2026
$6.1M
Name Molecular mechanisms of bacterial toxins targeting actin cytoskeletonR01GM114666 · NIGMS · OHIO STATE UNIVERSITY · PI KUDRYASHOV, DMITRI · 2015 to 2025
$3.8M
National Heart Lung and Blood Institute R01HL138579NHLBI NIH HHS R01 HL138579NIGMS NIH HHS R01 GM114666NIGMS NIH HHS R01GM114666NIGMS NIH HHS R35 GM122510NIGMS NIH HHS R35GM122510
6 · The paper itself

Abstract

Due to its essential role in cellular processes, actin is a common target for bacterial toxins. One such toxin, TccC3, is an effector domain of the ABC-toxin produced by entomopathogenic bacteria of

Indexed as

PhotorhabdusActin CytoskeletonActin Depolymerizing FactorsActinsAdenosine DiphosphateADP Ribose TransferasesActin Depolymerizing FactorsActinsAdenosine DiphosphateADP Ribose Transferasesactinactin dynamicsADP-ribosylationbacterial toxinblebbingcalponin-homology domainCryo-EMspontaneous nucleationTccC3

Identifiers

PMID35806028
PMCPMC9266650
OpenAlexW4283579367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.