Evidence map›Paper›PMID 35806001›Full record

ArticleInternational journal of molecular sciences2022

Recombinant Cathepsin L of

Elena A Dvoryakova, Maria A Klimova, Tatiana R Simonyan, Ivan A Dombrovsky, Marina V Serebryakova, Valeriia F Tereshchenkova, Yakov E Dunaevsky, Mikhail A Belozersky, Irina Y Filippova, Elena N Elpidina

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Cold-Adapted Proteases: An Efficient and Energy-Saving Biocatalyst.International journal of molecular sciences · 2023
    Review
  4. Peptidases: Role and Function in Health and Disease.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Elena A DvoryakovaA.N. Belozersky Institute of Physico-Chemical Biology, M.V. Lomonosov Moscow State University, 119991 Moscow, Russia.
Maria A KlimovaDepartment of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russia.
Tatiana R SimonyanDepartment of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0002-9291-877X
Ivan A DombrovskyDepartment of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russia.
Marina V SerebryakovaA.N. Belozersky Institute of Physico-Chemical Biology, M.V. Lomonosov Moscow State University, 119991 Moscow, Russia.
Valeriia F TereshchenkovaDepartment of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russia.
Yakov E DunaevskyA.N. Belozersky Institute of Physico-Chemical Biology, M.V. Lomonosov Moscow State University, 119991 Moscow, Russia.
Mikhail A BelozerskyA.N. Belozersky Institute of Physico-Chemical Biology, M.V. Lomonosov Moscow State University, 119991 Moscow, Russia.
Irina Y FilippovaDepartment of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russia.
Elena N ElpidinaA.N. Belozersky Institute of Physico-Chemical Biology, M.V. Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0002-4988-4842
Lomonosov Moscow State University · RU

Funding

Russian Foundation for Basic Research grant 20-54-56044 Iran_t.
6 · The paper itself

Abstract

Wheat gliadins contain a large amount of glutamine- and proline-rich peptides which are not hydrolyzed by human digestive peptidases and can cause autoimmune celiac disease and other forms of gluten intolerance in predisposed people. Peptidases that efficiently cleave such immunogenic peptides can be used in enzyme therapy. The stored product insect pest

Indexed as

Celiac DiseaseTriboliumAnimalsCathepsin LEnzyme PrecursorsGliadinGlutamineHumansHydrolysisPeptide HydrolasesPeptidesCathepsin LEnzyme PrecursorsGliadinGlutaminePeptide HydrolasesPeptidescathepsin Lcysteine peptidasesdigestive peptidasesgliadinsrecombinant enzymesTribolium castaneum

Identifiers

PMID35806001
PMCPMC9266932
OpenAlexW4283366158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.