Evidence map›Paper›PMID 35805479›Full record

SynthesisInternational journal of environmental research and public health2022

Effects of Polybrominated Diphenyl Ethers on Hormonal and Reproductive Health in E-Waste-Exposed Population: A Systematic Review.

Vishal Singh, Javier Cortes-Ramirez, Leisa-Maree Toms, Thilakshika Sooriyagoda, Shamshad Karatela

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Intervention Strategies usingEndocrine, metabolic & immune disorders drug targets · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Vishal SinghSchool of Public Health and Social Work, Queensland University of Technology, Brisbane, QLD 4059, Australia.ORCID 0000-0003-3364-6708
Javier Cortes-RamirezCentre for Data Science, Queensland University of Technology, Brisbane, QLD 4059, Australia.ORCID 0000-0002-5876-165X
Leisa-Maree TomsSchool of Public Health and Social Work, Queensland University of Technology, Brisbane, QLD 4059, Australia.ORCID 0000-0002-1444-1638
Thilakshika SooriyagodaSchool of Public Health and Social Work, Queensland University of Technology, Brisbane, QLD 4059, Australia.ORCID 0000-0002-9963-1173
Shamshad KaratelaSchool of Pharmacy, University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0001-7425-7229
Queensland University of Technology · AUThe University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electronic waste management is a global rising concern that is primarily being handled by informal recycling practices. These release a mix of potentially hazardous chemicals, which is an important public health concern. These chemicals include polybrominated diphenyl ethers (PBDEs), used as flame retardants in electronic parts, which are persistent in nature and show bioaccumulative characteristics. Although PBDEs are suspected endocrine disruptors, particularly targeting thyroid and reproductive hormone functions, the relationship of PBDEs with these health effects are not well established. We used the Navigation Guide methodology to conduct a systematic review of studies in populations exposed to e-waste to better understand the relationships of these persistent flame retardants with hormonal and reproductive health. We assessed nineteen studies that fit our pre-determined inclusion criteria for risk of bias, indirectness, inconsistency, imprecision, and other criteria that helped rate the overall evidence for its quality and strength of evidence. The studies suggest PBDEs may have an adverse effect on thyroid hormones, reproductive hormones, semen quality, and neonatal health. However, more research is required to establish a relationship of these effects in the e-waste-exposed population. We identified the limitations of the data available and made recommendations for future scientific work.

Indexed as

Electronic WasteFlame RetardantsHalogenated Diphenyl EthersReproductive HealthSemen AnalysisFlame RetardantsHalogenated Diphenyl Ethersendocrine-disrupting chemicalsenvironmental exposureflame retardantsnon-monotonic dose–responseoccupational healthpersistent organic pollutants (POPs)

Identifiers

PMID35805479
PMCPMC9265575
OpenAlexW4283522518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.