SynthesisInternational journal of environmental research and public health2022
The Impact of COVID-19 Infection on Cognitive Function and the Implication for Rehabilitation: A Systematic Review and Meta-Analysis.
Synthesis in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Definitions and symptoms of the post-COVID syndrome: an updated systematic umbrella review.European archives of psychiatry and clinical neuroscience · 2025Pooled it
- Pathophysiological Mechanisms in Long COVID: A Mixed Method Systematic Review.International journal of environmental research and public health · 2024Pooled it
- Topical Cellular/Tissue and Molecular Aspects Regarding Nonpharmacological Interventions in Alzheimer's Disease-A Systematic Review.International journal of molecular sciences · 2023Pooled it
- Psychopathological, neuropsychological and sociodemographic description of the population using a post-COVID outpatient clinic: results from the 2Long4COVID BLOOD study.European archives of psychiatry and clinical neuroscience · 2026Article
- Neurocognitive Impairment After COVID-19: Mechanisms, Phenotypes, and Links to Alzheimer's Disease.Brain sciences · 2025Review
- Long-term neuropsychological consequences of severe COVID-19 infection: the NEUROCOG-COVID study.Journal of neurology · 2025Article
- An Exploratory Analysis of Contributors to Cognitive Functioning Among Sexual and Gender Minority Individuals Who Had COVID-19.Journal of homosexuality · 2025Article
- A tablet-based intervention study to alleviate cognitive and psychological symptoms in patients with post-Covid-19 condition.Frontiers in psychology · 2025Article
- Factors associated with cognitive impairment and the quality-of-life among COVID-19 survivors working as healthcare workers.Narra J · 2024Article
- Spontaneous recovery from post-COVID-19 brain fog.PCN reports : psychiatry and clinical neurosciences · 2024Article
- Cognition and Memory after Covid-19 in a Large Community Sample.The New England journal of medicine · 2024Article
- "Brain Fog" After COVID-19 Infection: How the Field of Neuropsychology Can Help Clear the Air.Advances in experimental medicine and biology · 2024Article
- Clinical and serological predictors of post COVID-19 condition-findings from a Canadian prospective cohort study.Frontiers in public health · 2024Article
- Cognitive Aspects of COVID-19.Current neurology and neuroscience reports · 2023Review
- Persistent Cognitive Dysfunction in a Non-Hospitalized COVID-19 Long-Hauler Patient Responding to Cognitive Rehabilitation and Citicoline Treatment.Brain sciences · 2023Article
- Preserved perception-action integration in adolescents after a COVID-19 infection.Scientific reports · 2023Article
- The effects of COVID-19 on cognitive performance in a community-based cohort: a COVID symptom study biobank prospective cohort study.EClinicalMedicine · 2023Article
- Scientific Rationale for the Treatment of Cognitive Deficits from Long COVID.Neurology international · 2023Review
- Impact of COVID-19 infection on cognition and its association with neurological symptoms.Brain and behavior · 2023Article
- A Prospect to Ameliorate Affective Symptoms and to Enhance Cognition in Long COVID Using Auricular Transcutaneous Vagus Nerve Stimulation.Journal of clinical medicine · 2023Article
Corrections and comments
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Authors and funding
2 authors.
Funding
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Abstract
There is mounting evidence that patients with severe COVID-19 disease may have symptoms that continue beyond the acute phase, extending into the early chronic phase. This prolonged COVID-19 pathology is often referred to as 'Long COVID'. Simultaneously, case investigations have shown that COVID-19 individuals might have a variety of neurological problems. The accurate and accessible assessment of cognitive function in patients post-COVID-19 infection is thus of increasingly high importance for both public and individual health. Little is known about the influence of COVID-19 on the general cognitive levels but more importantly, at sub-functions level. Therefore, we first aim to summarize the current level of evidence supporting the negative impact of COVID-19 infection on cognitive functions. Twenty-seven studies were included in the systematic review representing a total of 94,103 participants (90,317 COVID-19 patients and 3786 healthy controls). We then performed a meta-analysis summarizing the results of five studies (959 participants, 513 patients) to quantify the impact of COVID-19 on cognitive functions. The overall effect, expressed in standardized mean differences, is -0.41 [95%CI -0.55; -0.27]. To prevent disability, we finally discuss the different approaches available in rehabilitation to help these patients and avoid long-term complications.
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