Evidence map›Paper›PMID 35805185›Full record

ReviewCells2022

Endogenous Neural Stem Cell Mediated Oligodendrogenesis in the Adult Mammalian Brain.

Daniel Z Radecki, Jayshree Samanta

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Daniel Z RadeckiDepartment of Comparative Biosciences, School of Veterinary Medicine, Stem Cell and Regenerative Medicine Center, University of Wisconsin-Madison, Madison, WI 53706, USA.
Jayshree SamantaDepartment of Comparative Biosciences, School of Veterinary Medicine, Stem Cell and Regenerative Medicine Center, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0003-1240-3395
University of Wisconsin–Madison · US

Funding

Novel Modulators of TGFß1 signaling in regulation of remyelination by neural stem cellsR01NS119517 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI Jayshree Samanta · 2022 to 2026
$1.8M
Role of GPNMB Signaling in Remyelination by Oligodendrocyte Progenitor CellsR03NS126993 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI SAMANTA, JAYSHREE · 2022 to 2023
$156k
NINDS NIH HHS R01 NS119517NINDS NIH HHS R03 NS126993
6 · The paper itself

Abstract

Oligodendrogenesis is essential for replacing worn-out oligodendrocytes, promoting myelin plasticity, and for myelin repair following a demyelinating injury in the adult mammalian brain. Neural stem cells are an important source of oligodendrocytes in the adult brain; however, there are considerable differences in oligodendrogenesis from neural stem cells residing in different areas of the adult brain. Amongst the distinct niches containing neural stem cells, the subventricular zone lining the lateral ventricles and the subgranular zone in the dentate gyrus of the hippocampus are considered the principle areas of adult neurogenesis. In addition to these areas, radial glia-like cells, which are the precursors of neural stem cells, are found in the lining of the third ventricle, where they are called tanycytes, and in the cerebellum, where they are called Bergmann glia. In this review, we will describe the contribution and regulation of each of these niches in adult oligodendrogenesis.

Indexed as

Neural Stem CellsAnimalsBrainCell DifferentiationLateral VentriclesMammalsNeurogenesisadult neural stem cellBergmann gliacerebellumoligodendrocyteoligodendrogenesissubgranular zonesubventricular zonetanycyte

Identifiers

PMID35805185
PMCPMC9265817
OpenAlexW4283781219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.