Evidence map›Paper›PMID 35805121›Full record

ArticleCells2022

PKC-Mediated Orai1 Channel Phosphorylation Modulates Ca

Ericka Martínez-Martínez, Víctor Hugo Sánchez-Vázquez, Daniel León-Aparicio, Jose Sanchez-Collado, Martín-Leonardo Gallegos-Gómez, Juan A Rosado, Juan M Arias, Agustin Guerrero-Hernández

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. [Research advances in genetic polymorphisms in Kawasaki disease].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023
    Article
  3. Kinetics of the thapsigargin-induced CaFrontiers in physiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Ericka Martínez-MartínezDepartment of Biochemistry, Cinvestav, Mexico City 07360, Mexico.
Víctor Hugo Sánchez-VázquezDepartment of Biochemistry, Cinvestav, Mexico City 07360, Mexico.
Daniel León-AparicioDepartment of Biochemistry, Cinvestav, Mexico City 07360, Mexico.
Jose Sanchez-ColladoCellular Physiology Research Group, Department of Physiology, Institute of Molecular Pathology Biomarkers, University of Extremadura, 10003 Caceres, Spain.
Martín-Leonardo Gallegos-GómezDepartment of Biochemistry, Cinvestav, Mexico City 07360, Mexico.
Juan A RosadoCellular Physiology Research Group, Department of Physiology, Institute of Molecular Pathology Biomarkers, University of Extremadura, 10003 Caceres, Spain.ORCID 0000-0002-9749-2325
Juan M AriasPrograma de Neurociencias-UIICSE, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla de Baz 54090, Mexico.
Agustin Guerrero-HernándezDepartment of Biochemistry, Cinvestav, Mexico City 07360, Mexico.ORCID 0000-0002-8653-4841
Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional · MXUniversidad de Extremadura · ESAutonomous University of San Luis Potosí · MXAutonomous University of Tlaxcala · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The overexpression of the Orai1 channel inhibits SOCE when using the Ca

Indexed as

CalciumCalcium ChannelsAdenosine TriphosphateHeLa CellsHumansORAI1 ProteinPhosphorylationProtein Kinase CThapsigarginAdenosine TriphosphateCalciumCalcium ChannelsORAI1 ProteinORAI1 protein, humanProtein Kinase CThapsigarginphosphomimeticphosphorylated Orai1PKCSOCE

Identifiers

PMID35805121
PMCPMC9266177
OpenAlexW4283657617

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.